arap1a ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arap1aprovided by ZNC
Official Full Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6226
See related: Ensembl:ENSDARG00000062221 AllianceGenome:ZFIN:ZDB-GENE-030131-6226
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi39f07; wu:fi39f07; si:ch211-135f11.1
Summary: Predicted to enable GTPase activator activity and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in regulation of actin cytoskeleton organization and regulation of cell projection organization. Predicted to act upstream of or within positive regulation of GTPase activity and signal transduction. Predicted to be active in cytoplasm. Orthologous to human ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (23888307..23909945, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (23384160..23406170, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol-3,4,5-trisphosphate binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Preferred Names: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

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The following sections contain reference sequences that belong to a specific genome build. Explain