aldh9a1b aldehyde dehydrogenase 9 family, member A1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aldh9a1bprovided by ZNC
Official Full Name: aldehyde dehydrogenase 9 family, member A1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040120-5
See related: Ensembl:ENSDARG00000037061 AllianceGenome:ZFIN:ZDB-GENE-040120-5
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: TMABADH; aldh9a1; TMABA-DH
Summary: Predicted to enable 4-trimethylammoniobutyraldehyde dehydrogenase activity and aminobutyraldehyde dehydrogenase (NAD+) activity. Predicted to be involved in cellular aldehyde metabolic process and protein homotetramerization. Predicted to be located in cytosol. Orthologous to human ALDH9A1 (aldehyde dehydrogenase 9 family member A1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (6067366..6092064)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (6155444..6180186)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 4-trimethylammoniobutyraldehyde dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 4-trimethylammoniobutyraldehyde dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables 4-trimethylammoniobutyraldehyde dehydrogenase activity	ISS Inferred from Sequence or Structural Similarity more info
enables aldehyde dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
enables aminobutyraldehyde dehydrogenase (NAD+) activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in aldehyde metabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in carnitine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in protein homotetramerization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 4-trimethylaminobutyraldehyde dehydrogenase B

Names: aldehyde dehydrogenase 9 family, member A1; aldehyde dehydrogenase 9A1b; aldehyde dehydrogenase family 9 member A1-B

NP_958916.1

EC 1.2.1.3

EC 1.2.1.47

XP_005163288.1

EC 1.2.1.3

EC 1.2.1.47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201508.1 → NP_958916.1 4-trimethylaminobutyraldehyde dehydrogenase B

See identical proteins and their annotated locations for NP_958916.1

Status: PROVISIONAL

Source sequence(s)

BC047176

UniProtKB/TrEMBL

A0A8M3AVP0, B2GT49

Related

ENSDARP00000053867.3, ENSDART00000053868.4

Conserved Domains (1) summary

cd07090
Location:55 → 512

ALDH_F9_TMBADH; NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007113.7 Reference GRCz11 Primary Assembly

Range

6067366..6092064

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005163231.5 → XP_005163288.1 4-trimethylaminobutyraldehyde dehydrogenase B isoform X1

See identical proteins and their annotated locations for XP_005163288.1

UniProtKB/Swiss-Prot

A2AWD6, Q802W2

UniProtKB/TrEMBL

A0A8M3AVP0

Conserved Domains (1) summary

cd07090
Location:55 → 512

ALDH_F9_TMBADH; NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1