nkl.4 NK-lysin tandem duplicate 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nkl.4provided by ZNC
Official Full Name: NK-lysin tandem duplicate 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7503
See related: Ensembl:ENSDARG00000044023 AllianceGenome:ZFIN:ZDB-GENE-030131-7503
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: nkld; wu:fj22b05; si:rp71-40n14.1
Summary: Predicted to act upstream of or within defense response to bacterium and lipid metabolic process. Is expressed in several structures, including caudal fin; gill; liver; myeloid cell; and pleuroperitoneal region. Orthologous to human GNLY (granulysin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (8854189..8862396, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (8697009..8705216, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within defense response to bacterium	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: NK-lysin tandem duplicate 4

Names: NK lysin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212741.1 → NP_997906.1 NK-lysin tandem duplicate 4 precursor

See identical proteins and their annotated locations for NP_997906.1

Status: PROVISIONAL

Source sequence(s)

AY184216

UniProtKB/TrEMBL

A0A0K1H3J2, F6P070, Q7T3Q1

Related

ENSDARP00000064632.4, ENSDART00000064633.5

Conserved Domains (3) summary

smart00741
Location:47 → 119

SapB; Saposin (B) Domains

pfam03489
Location:88 → 119

SapB_2; Saposin-like type B, region 2

pfam05184
Location:47 → 81

SapB_1; Saposin-like type B, region 1