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    mybpha myosin binding protein Ha [ Danio rerio (zebrafish) ]

    Gene ID: 393530, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mybphaprovided by ZNC
    Official Full Name
    myosin binding protein Haprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1531
    See related
    Ensembl:ENSDARG00000058799 AllianceGenome:ZFIN:ZDB-GENE-040426-1531
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66097; zgc:85883; zgc:91966
    Summary
    Predicted to be involved in sarcomere organization. Predicted to be active in M band. Is expressed in hypaxial myotome region; musculature system; myotome; pectoral fin; and somite. Orthologous to several human genes including MYBPH (myosin binding protein H). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mybpha in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (6077503..6126003)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (6143531..6191904)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene cysteine and glycine-rich protein 1a Neighboring gene neuron navigator 1a Neighboring gene basement membrane-specific heparan sulfate proteoglycan core protein Neighboring gene uncharacterized LOC101885725

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Zebrafish foxc1a drives appendage-specific neural circuit development. Banerjee S, et al. Development, 2015 Feb 15. PMID 25670796, Free PMC Article
    2. The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis. Hawkins TA, et al. Development, 2008 Mar. PMID 18256191, Free PMC Article
    3. Patterns of alternative splicing in response to cold acclimation in fish. Healy TM, et al. J Exp Biol, 2019 Mar 7. PMID 30692167
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC66097

    General protein information

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    Preferred Names
    myosin binding protein Ha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001331200.1 → NP_001318129.1  myosin binding protein Ha isoform 2

      Status: VALIDATED

      Source sequence(s)
      BC074055
      UniProtKB/TrEMBL
      A0A8M1PAK8, Q6GMJ2
      Related
      ENSDARP00000124440.1, ENSDART00000081714.6

    2. NM_200558.2 → NP_956852.2  myosin binding protein Ha isoform 1

      Status: VALIDATED

      Source sequence(s)
      BC067675, BC074055
      UniProtKB/TrEMBL
      A0A8M1PEL2, Q6NW94
      Related
      ENSDARP00000125046.1, ENSDART00000139834.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      6077503..6126003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353529.3 → XP_017209018.1  myosin binding protein Ha isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z3P8

    2. XM_017353530.3 → XP_017209019.1  myosin binding protein Ha isoform X2

      UniProtKB/TrEMBL
      A0A8M6YVU2
    Nucleotide Protein
    Heading Accession and Version

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