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    med18 mediator of RNA polymerase II transcription, subunit 18 homolog (yeast) [ Danio rerio (zebrafish) ]

    Gene ID: 393306, updated on 9-Dec-2024

    Summary

    Official Symbol
    med18provided by ZNC
    Official Full Name
    mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1276
    See related
    Ensembl:ENSDARG00000041237 AllianceGenome:ZFIN:ZDB-GENE-040426-1276
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:63855
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of transcription initiation by RNA polymerase II. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Orthologous to human MED18 (mediator complex subunit 18). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See med18 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (7376471..7379275, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (7459125..7461929, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene forkhead box O6 a Neighboring gene uncharacterized LOC137487874 Neighboring gene ATG5 autophagy related 5 homolog (S. cerevisiae) Neighboring gene PR domain containing 1a, with ZNF domain

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC63855

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 18
    Names
    mediator complex subunit 18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200335.1NP_956629.1  mediator of RNA polymerase II transcription subunit 18

      See identical proteins and their annotated locations for NP_956629.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053113
      UniProtKB/Swiss-Prot
      Q7T3H7
      Related
      ENSDARP00000060446.3, ENSDART00000060447.4
      Conserved Domains (1) summary
      pfam09637
      Location:19207
      Med18; Med18 protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      7376471..7379275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)