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    gpn2 GPN-loop GTPase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 407722, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gpn2provided by ZNC
    Official Full Name
    GPN-loop GTPase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041010-86
    See related
    Ensembl:ENSDARG00000103127 AllianceGenome:ZFIN:ZDB-GENE-041010-86
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    atpbd1b; zgc:92877
    Summary
    Predicted to enable GTPase activity. Orthologous to human GPN2 (GPN-loop GTPase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See gpn2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (33938213..33943728)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (33984047..33989698)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene G protein nucleolar 2 Neighboring gene dynein, axonemal, light intermediate chain 1 Neighboring gene Smad nuclear interacting protein Neighboring gene AT-rich interaction domain 1Aa Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class V

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Prepatterning of developmental gene expression by modified histones before zygotic genome activation. Lindeman LC, et al. Dev Cell, 2011 Dec 13. PMID 22137762
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC92877

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GPN-loop GTPase 2
    Names
    ATP-binding domain 1 family member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214801.2 → NP_999966.2  GPN-loop GTPase 2

      See identical proteins and their annotated locations for NP_999966.2

      Status: VALIDATED

      Source sequence(s)
      BC083538, BC152270, EB797177
      UniProtKB/Swiss-Prot
      Q5XIY1, Q6PUR6
      UniProtKB/TrEMBL
      A0A8M3AJ98, A7MCQ6
      Related
      ENSDARP00000138851.1, ENSDART00000166254.2
      Conserved Domains (2) summary
      COG1100
      Location:14 → 183
      Gem1; GTPase SAR1 family domain [General function prediction only]
      pfam03029
      Location:15 → 262
      ATP_bind_1; Conserved hypothetical ATP binding protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      33938213..33943728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009292455.4 → XP_009290730.1  GPN-loop GTPase 2 isoform X1

      See identical proteins and their annotated locations for XP_009290730.1

      UniProtKB/Swiss-Prot
      Q5XIY1, Q6PUR6
      UniProtKB/TrEMBL
      A0A8M3AJ98, A7MCQ6
      Related
      ENSDART00000162704.2
      Conserved Domains (2) summary
      COG1100
      Location:14 → 183
      Gem1; GTPase SAR1 family domain [General function prediction only]
      pfam03029
      Location:15 → 262
      ATP_bind_1; Conserved hypothetical ATP binding protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PUR6.1 GenPept UniProtKB/Swiss-Prot:Q6PUR6

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