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    slc32a1 solute carrier family 32 member 1 [ Danio rerio (zebrafish) ]

    Gene ID: 798575, updated on 9-Dec-2024

    Summary

    Official Symbol
    slc32a1provided by ZNC
    Official Full Name
    solute carrier family 32 member 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061201-1
    See related
    Ensembl:ENSDARG00000059775 AllianceGenome:ZFIN:ZDB-GENE-061201-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:158324
    Summary
    Predicted to enable glycine transmembrane transporter activity. Predicted to be involved in gamma-aminobutyric acid transport; glycine transport; and neurotransmitter loading into synaptic vesicle. Predicted to be located in membrane. Predicted to be active in dendrite terminus; neuron projection terminus; and synaptic vesicle membrane. Is expressed in brain; dorsal habenular nucleus; inhibitory interneuron; and spinal cord. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy and generalized epilepsy with febrile seizures plus. Orthologous to human SLC32A1 (solute carrier family 32 member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See slc32a1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (60142618..60147517, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (60147710..60152609, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene PRELI domain containing 3 Neighboring gene aurora kinase A Neighboring gene uncharacterized LOC137496034 Neighboring gene rho GTPase-activating protein 40

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC158324

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in gamma-aminobutyric acid transport  
    involved_in glycine transport  
    involved_in neurotransmitter loading into synaptic vesicle  
    Component Evidence Code Pubs
    is_active_in dendrite terminus  
    located_in membrane  
    is_active_in neuron projection terminus  
    is_active_in synaptic vesicle membrane  

    General protein information

    Preferred Names
    vesicular inhibitory amino acid transporter
    Names
    solute carrier family 32 (GABA vesicular transporter), member 1
    viaat

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080701.1 → NP_001074170.1  vesicular inhibitory amino acid transporter

      See identical proteins and their annotated locations for NP_001074170.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129202
      UniProtKB/TrEMBL
      A0A8M1NBM3, A1L1T3
      Related
      ENSDARP00000077888.4, ENSDART00000083453.7
      Conserved Domains (1) summary
      pfam01490
      Location:120 → 517
      Aa_trans; Transmembrane amino acid transporter protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      60142618..60147517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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