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    zgc:110843 zgc:110843 [ Danio rerio (zebrafish) ]

    Gene ID: 541492, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zgc:110843provided by ZNC
    Official Full Name
    zgc:110843provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050327-15
    See related
    Ensembl:ENSDARG00000073845 AllianceGenome:ZFIN:ZDB-GENE-050327-15
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable 2 iron, 2 sulfur cluster binding activity and L-cysteine transaminase activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to act upstream of or within regulation of autophagy. Predicted to be located in intracellular membrane-bounded organelle and membrane. Predicted to be active in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See zgc:110843 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (7902346..7916683)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (7596224..7610729)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 3, catalytic subunit, beta isozyme Neighboring gene ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) Neighboring gene CXXC finger protein 5b Neighboring gene uncharacterized LOC137487563 Neighboring gene zgc:92242

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-cysteine transaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in intracellular iron ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC541492

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014305.1 → NP_001014327.1  uncharacterized protein LOC541492

      See identical proteins and their annotated locations for NP_001014327.1

      Status: PREDICTED

      Source sequence(s)
      BC092000
      UniProtKB/TrEMBL
      A0A8M1N4K8, Q58EB0
      Related
      ENSDARP00000101688.2, ENSDART00000113299.4
      Conserved Domains (1) summary
      smart00704
      Location:68 → 106
      ZnF_CDGSH; CDGSH-type zinc finger. Function unknown

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      7902346..7916683
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157144.5 → XP_005157201.1  uncharacterized protein LOC541492 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B412
      Conserved Domains (1) summary
      smart00704
      Location:58 → 96
      ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    Nucleotide Protein Strain
    Heading Accession and Version

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