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    nip7 NIP7 nucleolar pre-rRNA processing protein [ Danio rerio (zebrafish) ]

    Gene ID: 553616, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nip7provided by ZNC
    Official Full Name
    NIP7 nucleolar pre-rRNA processing proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-256
    See related
    Ensembl:ENSDARG00000059075 AllianceGenome:ZFIN:ZDB-GENE-050522-256
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:110384
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to act upstream of or within ribosome assembly. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; immature eye; liver; nervous system; and segmental plate. Orthologous to human NIP7 (nucleolar pre-rRNA processing protein NIP7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nip7 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (5844305..5850765, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (5229552..5236012, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene si:ch73-167i17.6 Neighboring gene zinc finger DHHC-type palmitoyltransferase 7 Neighboring gene component of oligomeric golgi complex 8 Neighboring gene NIN1 (RPN12) binding protein 1 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Genetic Deletion of miR-430 Disrupts Maternal-Zygotic Transition and Embryonic Body Plan. Liu Y, et al. Front Genet, 2020. PMID 32849832, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC110384

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within ribosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    60S ribosome subunit biogenesis protein NIP7 homolog
    Names
    nuclear import 7 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020590.1 → NP_001018426.1  60S ribosome subunit biogenesis protein NIP7 homolog

      See identical proteins and their annotated locations for NP_001018426.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095238
      UniProtKB/Swiss-Prot
      Q503P2
      UniProtKB/TrEMBL
      B2GR20
      Related
      ENSDARP00000076524.4, ENSDART00000082087.6
      Conserved Domains (1) summary
      COG1374
      Location:1 → 177
      NIP7; Rbosome biogenesis protein Nip4, contains PUA domain [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      5844305..5850765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q503P2.1 GenPept UniProtKB/Swiss-Prot:Q503P2

    Gene LinkOut

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