hsf5 heat shock transcription factor family member 5 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hsf5provided by ZNC
Official Full Name: heat shock transcription factor family member 5provided by ZNC
Primary source: ZFIN:ZDB-GENE-070410-42
See related: Ensembl:ENSDARG00000104686 AllianceGenome:ZFIN:ZDB-GENE-070410-42
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:162225
Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within spermatogenesis. Predicted to be active in nucleus. Is expressed in sperm; spermatid; spermatocyte; spermatogonium; and testis. Orthologous to human HSF5 (heat shock transcription factor 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (3094980..3118673, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003334334.2 (48259..71592)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Hsf5 is required for progression through meiotic prophase 1 during spermatogenesis.
Title: Heat Shock Factor 5 Is Essential for Spermatogenesis in Zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: heat shock factor protein 5

Names: heat shock transcription factor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089476.1 → NP_001082945.1 heat shock factor protein 5

See identical proteins and their annotated locations for NP_001082945.1

Status: PROVISIONAL

Source sequence(s)

BC139552

UniProtKB/TrEMBL

A4QNW9, B7ZV10

Related

ENSDARP00000130593.1, ENSDART00000167554.2

Conserved Domains (1) summary

pfam00447
Location:35 → 119

HSF_DNA-bind; HSF-type DNA-binding

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

3094980..3118673 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068221042.1 → XP_068077143.1 heat shock factor protein 5 isoform X2

UniProtKB/TrEMBL

A4QNW9, B7ZV10
XM_068221041.1 → XP_068077142.1 heat shock factor protein 5 isoform X1
XM_068221043.1 → XP_068077144.1 heat shock factor protein 5 isoform X3
XM_068221040.1 → XP_068077141.1 heat shock factor protein 5 isoform X1