U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    naa15b N-alpha-acetyltransferase 15, NatA auxiliary subunit b [ Danio rerio (zebrafish) ]

    Gene ID: 334099, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    naa15bprovided by ZNC
    Official Full Name
    N-alpha-acetyltransferase 15, NatA auxiliary subunit bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6031
    See related
    Ensembl:ENSDARG00000030368 AllianceGenome:ZFIN:ZDB-GENE-030131-6031
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    narg1b; fi31d06; wu:fi31d06
    Summary
    Predicted to enable acetyltransferase activator activity. Acts upstream of or within myotome development. Predicted to be part of NatA complex. Predicted to be active in cytoplasm. Is expressed in eye; immature eye; midbrain; optic tectum; and somite. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 50. Orthologous to human NAA15 (N-alpha-acetyltransferase 15, NatA auxiliary subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See naa15b in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (40613297..40641474)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39895224..39923401)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene short coiled-coil protein a Neighboring gene calmegin Neighboring gene uncharacterized LOC137493459 Neighboring gene ras-related protein Rab-33B Neighboring gene wu:fc34e06

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Naa15 knockdown enhances c2c12 myoblast fusion and induces defects in zebrafish myotome morphogenesis. Monestier O, et al. Comp Biochem Physiol B Biochem Mol Biol, 2019 Feb. PMID 30502388
    2. Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses. Lui EY, et al. J Genet Genomics, 2016 Aug 20. PMID 27503704
    3. Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain. Huang L, et al. Sci Rep, 2019 Feb 12. PMID 30755680, Free PMC Article
    4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acetyltransferase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within myotome development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NatA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    N-alpha-acetyltransferase 15, NatA auxiliary subunit b
    Names
    NMDA receptor-regulated gene 1b
    transcriptional coactivator tubedown-100

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_203321.2 → NP_976066.2  N-alpha-acetyltransferase 15, NatA auxiliary subunit b

      Status: VALIDATED

      Source sequence(s)
      BX511216, CU856624, FO904879
      UniProtKB/TrEMBL
      A0A0R4I9S5, A0A8M1PEL4
      Related
      ENSDARP00000130499.2, ENSDART00000168067.2
      Conserved Domains (3) summary
      sd00006
      Location:82 → 108
      TPR; TPR repeat [structural motif]
      pfam12569
      Location:187 → 698
      NARP1; NMDA receptor-regulated protein 1
      pfam13414
      Location:82 → 145
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      40613297..40641474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools