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    strbp spermatid perinuclear RNA binding protein [ Danio rerio (zebrafish) ]

    Gene ID: 557957, updated on 9-Dec-2024

    Summary

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    Official Symbol
    strbpprovided by ZNC
    Official Full Name
    spermatid perinuclear RNA binding proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030729-18
    See related
    Ensembl:ENSDARG00000021455 AllianceGenome:ZFIN:ZDB-GENE-030729-18
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb627; si:ch211-232m7.1
    Summary
    Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Predicted to act upstream of or within cell differentiation and spermatogenesis. Predicted to be located in cytoplasm. Is expressed in heart tube; nervous system; neural tube; notochord; and pharyngeal arch 3-7 skeleton. Orthologous to human STRBP (spermatid perinuclear RNA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See strbp in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (9823708..10018138, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (9873503..10059916, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene ring finger and CCCH-type domains 2 Neighboring gene rab GTPase-activating protein 1 Neighboring gene probable G-protein coupled receptor 21 Neighboring gene uncharacterized LOC137490368 Neighboring gene SH2 domain containing 3Ca

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Systematic identification of A-to-I RNA editing in zebrafish development and adult organs. Buchumenski I, et al. Nucleic Acids Res, 2021 May 7. PMID 33872356, Free PMC Article
    2. Reverse genetic analysis of neurogenesis in the zebrafish retina. Pujic Z, et al. Dev Biol, 2006 May 15. PMID 16603149
    3. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. Tiefenbach J, et al. PLoS One, 2010 Mar 22. PMID 20339547, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    spermatid perinuclear RNA-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      9823708..10018138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223908.1 → XP_068080009.1  spermatid perinuclear RNA-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8M2B2I0

    2. XM_021479265.2 → XP_021334940.1  spermatid perinuclear RNA-binding protein isoform X1

      UniProtKB/TrEMBL
      A0A8M2B247
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:403 → 467
      DSRM; Double-stranded RNA binding motif

    3. XM_021479266.2 → XP_021334941.1  spermatid perinuclear RNA-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8M2B2I0
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:402 → 466
      DSRM; Double-stranded RNA binding motif

    4. XM_021479264.2 → XP_021334939.1  spermatid perinuclear RNA-binding protein isoform X1

      UniProtKB/TrEMBL
      A0A8M2B247
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:403 → 467
      DSRM; Double-stranded RNA binding motif

    5. XM_068223910.1 → XP_068080011.1  spermatid perinuclear RNA-binding protein isoform X4

      UniProtKB/TrEMBL
      A0A8M2B2D0

    6. XM_068223909.1 → XP_068080010.1  spermatid perinuclear RNA-binding protein isoform X3

      UniProtKB/TrEMBL
      A0A8N7TC42, F1QB35, F1R194
      Related
      ENSDARP00000106616.3, ENSDART00000130734.3

    7. XM_021479268.2 → XP_021334943.1  spermatid perinuclear RNA-binding protein isoform X4

      UniProtKB/TrEMBL
      A0A8M2B2D0
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:402 → 466
      DSRM; Double-stranded RNA binding motif

    8. XM_021479267.2 → XP_021334942.1  spermatid perinuclear RNA-binding protein isoform X3

      UniProtKB/TrEMBL
      A0A8N7TC42, F1QB35, F1R194
      Related
      ENSDARP00000104616.2, ENSDART00000129151.4
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:403 → 467
      DSRM; Double-stranded RNA binding motif

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394771.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      15022..196727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068218568.1 → XP_068074669.1  spermatid perinuclear RNA-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8M2B2I0

    2. XM_005155604.5 → XP_005155661.1  spermatid perinuclear RNA-binding protein isoform X1

      See identical proteins and their annotated locations for XP_005155661.1

      UniProtKB/TrEMBL
      A0A8M2B247
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:403 → 467
      DSRM; Double-stranded RNA binding motif

    3. XM_005155605.5 → XP_005155662.1  spermatid perinuclear RNA-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8M2B2I0
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:402 → 466
      DSRM; Double-stranded RNA binding motif

    4. XM_005155603.5 → XP_005155660.1  spermatid perinuclear RNA-binding protein isoform X1

      See identical proteins and their annotated locations for XP_005155660.1

      UniProtKB/TrEMBL
      A0A8M2B247
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:403 → 467
      DSRM; Double-stranded RNA binding motif

    5. XM_068218570.1 → XP_068074671.1  spermatid perinuclear RNA-binding protein isoform X4

      UniProtKB/TrEMBL
      A0A8M2B2D0

    6. XM_068218569.1 → XP_068074670.1  spermatid perinuclear RNA-binding protein isoform X3

      UniProtKB/TrEMBL
      A0A8N7TC42, F1QB35, F1R194

    7. XM_005155606.5 → XP_005155663.1  spermatid perinuclear RNA-binding protein isoform X4

      UniProtKB/TrEMBL
      A0A8M2B2D0
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:402 → 466
      DSRM; Double-stranded RNA binding motif

    8. XM_701955.9 → XP_707047.3  spermatid perinuclear RNA-binding protein isoform X3

      UniProtKB/TrEMBL
      A0A8N7TC42, F1QB35, F1R194
      Conserved Domains (2) summary
      smart00572
      Location:97 → 350
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00358
      Location:403 → 467
      DSRM; Double-stranded RNA binding motif
    Nucleotide Protein Strain
    Heading Accession and Version

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