U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gtf3aa general transcription factor IIIAa [ Danio rerio (zebrafish) ]

    Gene ID: 445389, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    gtf3aaprovided by ZNC
    Official Full Name
    general transcription factor IIIAaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041006-1
    See related
    Ensembl:ENSDARG00000030267 AllianceGenome:ZFIN:ZDB-GENE-041006-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gtf3a; TFIIIA; zgc:111799
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be active in nucleus. Is expressed in brain; muscle; ovary; and testis. Orthologous to human GTF3A (general transcription factor IIIA). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See gtf3aa in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (67980191..67993075, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (67301648..67315381, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene GS homeobox 1 Neighboring gene mitochondrial translational initiation factor 3 Neighboring gene WASP family member 3a Neighboring gene ring finger protein 167

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Duplication and subfunctionalisation of the general transcription factor IIIA (gtf3a) gene in teleost genomes, with ovarian specific transcription of gtf3ab. Rojo-Bartolomé I, et al. PLoS One, 2020. PMID 31999691, Free PMC Article
    2. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    general transcription factor IIIAa
    Names
    transcription factor IIIA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003866.1 → NP_001003866.1  general transcription factor IIIAa

      See identical proteins and their annotated locations for NP_001003866.1

      Status: PROVISIONAL

      Source sequence(s)
      AY648780
      UniProtKB/TrEMBL
      Q6DRH9
      Related
      ENSDARP00000049330.5, ENSDART00000049331.7
      Conserved Domains (2) summary
      COG5048
      Location:58 → 226
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:114 → 133
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      67980191..67993075 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.