nop53 NOP53 ribosome biogenesis factor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nop53provided by ZNC
Official Full Name: NOP53 ribosome biogenesis factorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-051120-21
See related: Ensembl:ENSDARG00000100452 AllianceGenome:ZFIN:ZDB-GENE-051120-21
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb60b03; gltscr2; wu:fb60b03; zgc:123178
Summary: Predicted to enable 5S rRNA binding activity. Predicted to be involved in rRNA processing and ribosomal large subunit assembly. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human NOP53 (NOP53 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (6652431..6666232)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (6655108..6669139)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb60b03.x1 (e-PCR)
- UniSTS:203359

fl02c02.x1 (e-PCR)
- UniSTS:201855

fb60b03 (e-PCR)
- UniSTS:187278

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 5S rRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal large subunit assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ribosome biogenesis protein NOP53

Names: glioma tumor suppressor candidate region gene 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.