mindy1 MINDY lysine 48 deubiquitinase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mindy1provided by ZNC
Official Full Name: MINDY lysine 48 deubiquitinase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-070717-2
See related: Ensembl:ENSDARG00000004866 AllianceGenome:ZFIN:ZDB-GENE-070717-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fam63a; si:ch211-210h11.5
Summary: Predicted to enable K48-linked polyubiquitin modification-dependent protein binding activity. Predicted to act upstream of or within proteolysis. Orthologous to human MINDY1 (MINDY lysine 48 deubiquitinase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (7453996..7478597)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (7534951..7559672)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fc55b01.y1 (e-PCR)
- UniSTS:194073

fj41c04.y1 (e-PCR)
- UniSTS:199306

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables K48-linked deubiquitinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables K48-linked deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables K48-linked polyubiquitin modification-dependent protein binding	ISS Inferred from Sequence or Structural Similarity more info
enables cysteine-type carboxypeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables cysteine-type deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables cysteine-type peptidase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ubiquitin carboxyl-terminal hydrolase MINDY-1

Names: Protein FAM63A; deubiquitinating enzyme MINDY-1; family with sequence similarity 63, member A

NP_001093481.1

EC 3.4.19.12

XP_005159508.1

EC 3.4.19.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.