u2surp U2 snRNP-associated SURP domain containing [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: u2surpprovided by ZNC
Official Full Name: U2 snRNP-associated SURP domain containingprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070912-400
See related: Ensembl:ENSDARG00000061490 AllianceGenome:ZFIN:ZDB-GENE-070912-400
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fa03e02; wu:fb38b01; wu:fc75d03; si:dkey-181m9.9; mp:zf637-1-000918
Summary: Predicted to enable RNA binding activity. Predicted to act upstream of or within RNA processing. Predicted to be active in nucleus. Orthologous to human U2SURP (U2 snRNP associated SURP domain containing). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (26623377..26642870, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (26967742..26987310, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb38b01 (e-PCR)
- UniSTS:187147

fk47a05.x1 (e-PCR)
- UniSTS:201037

fc75d03.x1 (e-PCR)
- UniSTS:188258

fa03e02.s1 (e-PCR)
- UniSTS:202170

G47509 (e-PCR)
- UniSTS:108285

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: U2 snRNP-associated SURP motif-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001197074.1 → NP_001184003.1 U2 snRNP-associated SURP motif-containing protein

Status: VALIDATED

Source sequence(s)

BX248497

UniProtKB/TrEMBL

A0A8M1NW63, E9QCG7

Related

ENSDARP00000082147.5, ENSDART00000087714.7

Conserved Domains (4) summary

cd12223
Location:207 → 290

RRM_SR140; RNA recognition motif (RRM) in U2-associated protein SR140 and similar proteins

pfam01805
Location:364 → 412

Surp; Surp module

pfam08312
Location:782 → 823

cwf21; cwf21 domain

cl02544
Location:476 → 611

VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007113.7 Reference GRCz11 Primary Assembly

Range

26623377..26642870 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068224732.1 → XP_068080833.1 U2 snRNP-associated SURP motif-containing protein isoform X2

UniProtKB/TrEMBL

A0A8M3AQ85
XM_005163401.4 → XP_005163458.1 U2 snRNP-associated SURP motif-containing protein isoform X1

UniProtKB/TrEMBL

A0A8M2BAU2

Conserved Domains (4) summary

cd12223
Location:195 → 278

RRM_SR140; RNA recognition motif (RRM) in U2-associated protein SR140 and similar proteins

pfam01805
Location:352 → 400

Surp; Surp module

pfam08312
Location:770 → 811

cwf21; cwf21 domain

cl02544
Location:464 → 599

VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...