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    rhov ras homolog family member V [ Danio rerio (zebrafish) ]

    Gene ID: 100005849, updated on 9-Dec-2024

    Summary

    Official Symbol
    rhovprovided by ZNC
    Official Full Name
    ras homolog family member Vprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031002-10
    See related
    Ensembl:ENSDARG00000070434 AllianceGenome:ZFIN:ZDB-GENE-031002-10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb832; zgc:111951; si:ch211-244p18.1
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within epiboly involved in gastrulation with mouth forming second and protein localization to adherens junction. Predicted to be active in plasma membrane. Is expressed in several structures, including blastoderm; notochord; segmental plate; solid lens vesicle; and yolk syncytial layer. Orthologous to human RHOV (ras homolog family member V). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See rhov in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (28364741..28368127)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (28465651..28469037)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene INO80 complex ATPase subunit Neighboring gene VPS18 core subunit of CORVET and HOPS complexes Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class H Neighboring gene zinc finger, FYVE domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC111951, MGC174618

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Cdc42 protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within epiboly involved in gastrulation with mouth forming second IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in establishment of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein localization to adherens junction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    rho-related GTP-binding protein RhoV
    Names
    ras homolog gene family, member V

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012250.2NP_001012250.1  rho-related GTP-binding protein RhoV

      See identical proteins and their annotated locations for NP_001012250.1

      Status: PROVISIONAL

      Source sequence(s)
      BC154349
      UniProtKB/TrEMBL
      A8KC41, Q5YLG6
      Related
      ENSDARP00000094132.3, ENSDART00000103355.4
      Conserved Domains (2) summary
      cd04130
      Location:30193
      Wrch_1; Wnt-1 responsive Cdc42 homolog (Wrch-1) is a Rho family GTPase similar to Cdc42
      smart00174
      Location:32193
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      28364741..28368127
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)