rnf103 ring finger protein 103 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rnf103provided by ZNC
Official Full Name: ring finger protein 103provided by ZNC
Primary source: ZFIN:ZDB-GENE-040912-171
See related: Ensembl:ENSDARG00000100850 AllianceGenome:ZFIN:ZDB-GENE-040912-171
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92077
Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in ERAD pathway and protein ubiquitination. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human RNF103 (ring finger protein 103). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (16083854..16091862)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (15778291..15786299)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin-protein transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase RNF103

NP_001004600.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004600.1 → NP_001004600.1 E3 ubiquitin-protein ligase RNF103

See identical proteins and their annotated locations for NP_001004600.1

Status: PROVISIONAL

Source sequence(s)

BC081585

UniProtKB/TrEMBL

A0A8M1N256, Q66I18

Related

ENSDARP00000138760.1, ENSDART00000168462.2

Conserved Domains (2) summary

cd00162
Location:593 → 636

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

pfam13848
Location:192 → 318

Thioredoxin_6; Thioredoxin-like domain