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    crata carnitine O-acetyltransferase a [ Danio rerio (zebrafish) ]

    Gene ID: 449545, updated on 9-Dec-2024

    Summary

    Official Symbol
    crataprovided by ZNC
    Official Full Name
    carnitine O-acetyltransferase aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040927-17
    See related
    Ensembl:ENSDARG00000040248 AllianceGenome:ZFIN:ZDB-GENE-040927-17
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zeh0248; zgc:92317; hm:zeh0248
    Summary
    Predicted to enable carnitine O-acetyltransferase activity. Predicted to be involved in carnitine metabolic process, CoA-linked. Predicted to be active in peroxisome. Is expressed in cardiac ventricle. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Orthologous to human CRAT (carnitine O-acetyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See crata in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (32816201..32831036)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32216048..32230883)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene immediate early response 5-like Neighboring gene protein phosphatase 2 phosphatase activator Neighboring gene FKBP prolyl isomerase family member 15a Neighboring gene leucine rich repeat and sterile alpha motif containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables carnitine O-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables carnitine O-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carnitine metabolic process, CoA-linked IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    carnitine O-acetyltransferase
    NP_001005587.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005587.1NP_001005587.1  carnitine O-acetyltransferase

      See identical proteins and their annotated locations for NP_001005587.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081647
      UniProtKB/TrEMBL
      A0A8M1N2J8, Q642H6
      Related
      ENSDARP00000146631.1, ENSDART00000181535.1
      Conserved Domains (1) summary
      pfam00755
      Location:40620
      Carn_acyltransf; Choline/Carnitine o-acyltransferase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      32816201..32831036
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394586.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      317935..332770
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395240.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      78224..93059
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)