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    phb2b prohibitin 2b [ Danio rerio (zebrafish) ]

    Gene ID: 436954, updated on 9-Dec-2024

    Summary

    Official Symbol
    phb2bprovided by ZNC
    Official Full Name
    prohibitin 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-430
    See related
    Ensembl:ENSDARG00000017728 AllianceGenome:ZFIN:ZDB-GENE-040718-430
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:86841
    Summary
    Predicted to be involved in mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and solid lens vesicle. Orthologous to human PHB2 (prohibitin 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See phb2b in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (29707123..29714339)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (29716562..29723778)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 5-like a Neighboring gene phosphodiesterase 6D, cGMP-specific, rod, delta Neighboring gene uncharacterized LOC101886554 Neighboring gene prothymosin alpha a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002681.2NP_001002681.2  prohibitin-2b

      Status: VALIDATED

      Source sequence(s)
      EB786418, EH508828, EH518571, EH533427
      UniProtKB/TrEMBL
      A0A8M1N0W4, F1R9C6
      Related
      ENSDARP00000022440.6, ENSDART00000023549.7
      Conserved Domains (2) summary
      smart00244
      Location:49209
      PHB; prohibitin homologues
      cd03401
      Location:49243
      SPFH_prohibitin; Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      29707123..29714339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395256.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      253251..260467
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_4

    Genomic

    1. NW_018395387.1 Reference GRCz11 ALT_DRER_TU_4

      Range
      220037..227188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)