alg9 ALG9 alpha-1,2-mannosyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: alg9provided by ZNC
Official Full Name: ALG9 alpha-1,2-mannosyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1270
See related: Ensembl:ENSDARG00000012840 AllianceGenome:ZFIN:ZDB-GENE-040426-1270
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63820
Summary: Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in central nervous system; epiphysis; polster; and retina. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Il. Orthologous to human ALG9 (ALG9 alpha-1,2-mannosyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (57743815..57763183)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (57073581..57092966)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables hexosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: alpha-1,2-mannosyltransferase ALG9

Names: asparagine-linked glycosylation 9 homolog (S. cerevisiae, alpha- 1,2-mannosyltransferase)

NP_956919.2

EC 2.4.1.-

XP_009300116.2

EC 2.4.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200625.2 → NP_956919.2 alpha-1,2-mannosyltransferase ALG9

Status: VALIDATED

Source sequence(s)

BX901896, EH592472, EH609977

UniProtKB/TrEMBL

A0A8M1PER2, A0A8M3AZY9, A5PMV6

Related

ENSDARP00000017149.7, ENSDART00000005090.9

Conserved Domains (1) summary

pfam03901
Location:64 → 486

Glyco_transf_22; Alg9-like mannosyltransferase family