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    dusp16 dual specificity phosphatase 16 [ Danio rerio (zebrafish) ]

    Gene ID: 406523, updated on 9-Dec-2024

    Summary

    Official Symbol
    dusp16provided by ZNC
    Official Full Name
    dual specificity phosphatase 16provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2360
    See related
    Ensembl:ENSDARG00000102474 AllianceGenome:ZFIN:ZDB-GENE-040426-2360
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77247; wu:fi04g09
    Summary
    Predicted to enable MAP kinase tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; and protein tyrosine/threonine phosphatase activity. Predicted to be involved in negative regulation of MAPK cascade and signal transduction. Predicted to act upstream of or within protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human DUSP16 (dual specificity phosphatase 16). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See dusp16 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (107287..119689, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (149956..162126)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene MANSC domain containing 1 Neighboring gene low density lipoprotein receptor-related protein 6 Neighboring gene cAMP responsive element binding protein-like 2 Neighboring gene G protein-coupled receptor 19

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables MAP kinase tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables MAP kinase tyrosine/serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    dual specificity protein phosphatase 16
    NP_998405.2
    XP_068075676.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213240.2NP_998405.2  dual specificity protein phosphatase 16

      Status: VALIDATED

      Source sequence(s)
      FP085386
      UniProtKB/TrEMBL
      A0A8M1PEU4, F1RDV6
      Related
      ENSDARP00000137551.1, ENSDART00000161055.3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      107287..119689 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068219575.1XP_068075676.1  dual specificity protein phosphatase 16 isoform X1

      UniProtKB/TrEMBL
      A0A8M1PEU4, F1RDV6