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    cldn8.2 claudin 8.2 [ Danio rerio (zebrafish) ]

    Gene ID: 550497, updated on 9-Dec-2024

    Summary

    Official Symbol
    cldn8.2provided by ZNC
    Official Full Name
    claudin 8.2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-331
    See related
    Ensembl:ENSDARG00000040628 AllianceGenome:ZFIN:ZDB-GENE-050417-331
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cldn8d; sb:cb574; zgc:110333
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in anchoring junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in several structures, including EVL; epidermis; gill; periderm; and spleen. Orthologous to human CLDN17 (claudin 17) and CLDN8 (claudin 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cldn8.2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (42560354..42575210)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (42604012..42618868)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene SR-related CTD-associated factor 4b Neighboring gene TIAM Rac1 associated GEF 1b Neighboring gene claudin 8.3 Neighboring gene uncharacterized LOC103908871 Neighboring gene claudin 8.1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC550497
    Names
    claudin 8-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017799.2NP_001017799.1  uncharacterized protein LOC550497

      See identical proteins and their annotated locations for NP_001017799.1

      Status: PREDICTED

      Source sequence(s)
      BC129277
      UniProtKB/TrEMBL
      A1L1Z4, F6P0L2, Q568F1
      Related
      ENSDARP00000059483.5, ENSDART00000059484.7
      Conserved Domains (1) summary
      cl21598
      Location:62236
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      42560354..42575210
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)