U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cdc37 cell division cycle 37 homolog (S. cerevisiae) [ Danio rerio (zebrafish) ]

    Gene ID: 394013, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cdc37provided by ZNC
    Official Full Name
    cell division cycle 37 homolog (S. cerevisiae)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-940
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040426-940
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56210
    Summary
    Predicted to enable several functions, including heat shock protein binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding and protein stabilization. Predicted to act upstream of or within cell division. Predicted to be located in cytoplasm. Orthologous to human CDC37 (cell division cycle 37, HSP90 cochaperone). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cdc37 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (59007318..59014359)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (58438370..58450110)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003334099.1 (4916..8644)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882962 Neighboring gene general transcription factor 3C polypeptide 1 Neighboring gene glutamyl-tRNA synthetase 2, mitochondrial Neighboring gene uncharacterized LOC137494327

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Regulation of zebrafish heart regeneration by miR-133. Yin VP, et al. Dev Biol, 2012 May 15. PMID 22374218, Free PMC Article
    2. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC56210

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables heat shock protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-folding chaperone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein stabilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    hsp90 co-chaperone Cdc37

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201038.1 → NP_957332.1  hsp90 co-chaperone Cdc37

      See identical proteins and their annotated locations for NP_957332.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045994
      UniProtKB/TrEMBL
      Q7ZV56
      Conserved Domains (3) summary
      smart01071
      Location:4 → 128
      CDC37_N; Cdc37 N terminal kinase binding
      smart01069
      Location:287 → 367
      CDC37_C; Cdc37 C terminal domain
      smart01070
      Location:127 → 275
      CDC37_M; Cdc37 Hsp90 binding domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      59007318..59014359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.