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    AK2 adenylate kinase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 280716, updated on 30-Jan-2025

    Summary

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    Official Symbol
    AK2provided by VGNC
    Official Full Name
    adenylate kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:25771
    See related
    BGD:BT26044; EnsemblRapid:ENSBTAG00070008728
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See AK2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (120653550..120677181)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 62 Neighboring gene uncharacterized LOC112443186 Neighboring gene antizyme inhibitor 2 Neighboring gene uncharacterized LOC112443187 Neighboring gene uncharacterized LOC132343387 Neighboring gene microRNA mir-2357 Neighboring gene ring finger protein 19B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. The structure of bovine mitochondrial adenylate kinase: comparison with isoenzymes in other compartments. Schlauderer GJ, et al. Protein Sci, 1996 Mar. PMID 8868479, Free PMC Article
    2. Isolation and characterization of two types of cDNA for mitochondrial adenylate kinase and their expression in Escherichia coli. Kishi F, et al. J Biol Chem, 1987 Aug 25. PMID 3040716
    3. Mitochondrial adenylate kinase (AK2) from bovine heart. The complete primary structure. Frank R, et al. Eur J Biochem, 1986 Jan 2. PMID 3002789
    4. Isolation and characterization of the gene encoding bovine adenylate kinase isozyme 2. Tanaka H, et al. Gene, 1990 Sep 14. PMID 2227435
    5. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC137216

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables adenylate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ADP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenylate kinase 2, mitochondrial
    Names
    AK 2
    ATP-AMP transphosphorylase 2
    ATP:AMP phosphotransferase
    adenylate kinase isozyme 2
    adenylate monophosphate kinase
    NP_776314.1
    XP_005202939.1
    XP_024853981.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173889.1 → NP_776314.1  adenylate kinase 2, mitochondrial

      See identical proteins and their annotated locations for NP_776314.1

      Status: PROVISIONAL

      Source sequence(s)
      M16225
      UniProtKB/TrEMBL
      A0AAA9TLU8
      Related
      ENSBTAP00070011672.1, ENSBTAT00070019697.1
      Conserved Domains (1) summary
      pfam00406
      Location:22 → 206
      ADK; Adenylate kinase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      120653550..120677181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202882.3 → XP_005202939.1  adenylate kinase 2, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005202939.1

      UniProtKB/Swiss-Prot
      P08166, P08167, Q2KIJ7
      UniProtKB/TrEMBL
      A0AAA9TLU8
      Related
      ENSBTAP00070011693.1, ENSBTAT00070019728.1
      Conserved Domains (1) summary
      pfam00406
      Location:22 → 206
      ADK; Adenylate kinase

    2. XM_024998213.2 → XP_024853981.1  adenylate kinase 2, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0AAA9T6Y9
      Related
      ENSBTAP00070011650.1, ENSBTAT00070019659.1
      Conserved Domains (1) summary
      cl27057
      Location:22 → 118
      ADK; Adenylate kinase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P08166.2 GenPept UniProtKB/Swiss-Prot:P08166

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