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    KCND1 potassium voltage-gated channel subfamily D member 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 518384, updated on 1-Jan-2025

    Summary

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    Official Symbol
    KCND1provided by VGNC
    Official Full Name
    potassium voltage-gated channel subfamily D member 1provided by VGNC
    Primary source
    VGNC:VGNC:30434
    See related
    Ensembl:ENSBTAG00000009024
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See KCND1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (87068162..87076655, complement)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene Pim-2 proto-oncogene, serine/threonine kinase Neighboring gene OTU deubiquitinase 5 Neighboring gene GRIP1 associated protein 1 Neighboring gene uncharacterized LOC112445237

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables A-type (transient outward) potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated potassium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A-type voltage-gated potassium channel KCND1
    Names
    potassium voltage-gated channel, Shal-related subfamily, member 1
    voltage-gated potassium channel subunit Kv4.1
    voltage-gated shal-type potassium channel member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024553.1 → NP_001019724.1  A-type voltage-gated potassium channel KCND1

      See identical proteins and their annotated locations for NP_001019724.1

      Status: PROVISIONAL

      Source sequence(s)
      AY989810
      UniProtKB/Swiss-Prot
      Q52PG9
      Related
      ENSBTAP00000011882.4, ENSBTAT00000011882.6
      Conserved Domains (4) summary
      pfam11601
      Location:3 → 28
      Shal-type; Shal-type voltage-gated potassium channels, N-terminal
      pfam00520
      Location:185 → 417
      Ion_trans; Ion transport protein
      pfam02214
      Location:42 → 131
      BTB_2; BTB/POZ domain
      pfam11879
      Location:447 → 550
      DUF3399; Domain of unknown function (DUF3399)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      87068162..87076655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010821905.4 → XP_010820207.1  A-type voltage-gated potassium channel KCND1 isoform X1

      See identical proteins and their annotated locations for XP_010820207.1

      UniProtKB/Swiss-Prot
      Q52PG9
      Conserved Domains (4) summary
      pfam11601
      Location:3 → 28
      Shal-type; Shal-type voltage-gated potassium channels, N-terminal
      pfam00520
      Location:185 → 417
      Ion_trans; Ion transport protein
      pfam02214
      Location:42 → 131
      BTB_2; BTB/POZ domain
      pfam11879
      Location:447 → 550
      DUF3399; Domain of unknown function (DUF3399)

    2. XM_024988006.2 → XP_024843774.1  A-type voltage-gated potassium channel KCND1 isoform X1

      UniProtKB/Swiss-Prot
      Q52PG9
      Conserved Domains (4) summary
      pfam11601
      Location:3 → 28
      Shal-type; Shal-type voltage-gated potassium channels, N-terminal
      pfam00520
      Location:185 → 417
      Ion_trans; Ion transport protein
      pfam02214
      Location:42 → 131
      BTB_2; BTB/POZ domain
      pfam11879
      Location:447 → 550
      DUF3399; Domain of unknown function (DUF3399)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q52PG9.1 GenPept UniProtKB/Swiss-Prot:Q52PG9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.