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    SLC8B1 solute carrier family 8 member B1 [ Bos taurus (domestic cattle) ]

    Gene ID: 508887, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SLC8B1provided by VGNC
    Official Full Name
    solute carrier family 8 member B1provided by VGNC
    Primary source
    VGNC:VGNC:34938
    See related
    BGD:BT12062; Ensembl:ENSBTAG00000011103
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    SLC24A6
    Orthologs
    human mouse all
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    Genomic context

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    See SLC8B1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (61286703..61316709, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene IQ motif containing D Neighboring gene two pore segment channel 1 Neighboring gene 2'-5'-oligoadenylate synthetase 2 Neighboring gene 2',5'-oligoadenylate synthetase 1, 40/46kDa Neighboring gene 2',5'-oligoadenylate synthetase 1, 40/46kDa

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Discovery of eight novel divergent homologs expressed in cattle placenta. Larson JH, et al. Physiol Genomics, 2006 May 16. PMID 16554549
    2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium:sodium antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium export from the mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial sodium/calcium exchanger protein
    Names
    solute carrier family 24 (sodium/potassium/calcium exchanger), member 6
    solute carrier family 24 member 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177596.1 → NP_001171067.1  mitochondrial sodium/calcium exchanger protein precursor

      See identical proteins and their annotated locations for NP_001171067.1

      Status: VALIDATED

      Source sequence(s)
      BF889830, BT026307, DN282700, DY054190, FE008185, NKLS02000017
      UniProtKB/TrEMBL
      F1MSI3
      Related
      ENSBTAP00000029531.6, ENSBTAT00000029532.6
      Conserved Domains (1) summary
      pfam01699
      Location:421 → 545
      Na_Ca_ex; Sodium/calcium exchanger protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      61286703..61316709 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059875938.1 → XP_059731921.1  mitochondrial sodium/calcium exchanger protein isoform X1

      UniProtKB/TrEMBL
      F1MSI3

    2. XM_059875942.1 → XP_059731925.1  mitochondrial sodium/calcium exchanger protein isoform X4

      UniProtKB/TrEMBL
      A0A3Q1LSB1
      Related
      ENSBTAP00000063230.2, ENSBTAT00000070502.2

    3. XM_059875940.1 → XP_059731923.1  mitochondrial sodium/calcium exchanger protein isoform X2

      UniProtKB/TrEMBL
      F1MSI3

    4. XM_059875939.1 → XP_059731922.1  mitochondrial sodium/calcium exchanger protein isoform X1

      UniProtKB/TrEMBL
      F1MSI3

    5. XM_059875941.1 → XP_059731924.1  mitochondrial sodium/calcium exchanger protein isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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