U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PKNOX1 PBX/knotted 1 homeobox 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 533382, updated on 30-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    PKNOX1provided by VGNC
    Official Full Name
    PBX/knotted 1 homeobox 1provided by VGNC
    Primary source
    VGNC:VGNC:32948
    See related
    BGD:BT29891; EnsemblRapid:ENSBTAG00070030686
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PKNOX1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (143160275..143204710)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 4 Neighboring gene NADH:ubiquinone oxidoreductase subunit V3 Neighboring gene uncharacterized LOC132345932 Neighboring gene cystathionine beta-synthase Neighboring gene U2 small nuclear RNA auxiliary factor 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC137943

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    homeobox protein PKNOX1
    Names
    PBX/Knox1-related homeodomain containing polypeptide
    PBX/knotted homeobox 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046350.1 → NP_001039815.1  homeobox protein PKNOX1

      See identical proteins and their annotated locations for NP_001039815.1

      Status: PROVISIONAL

      Source sequence(s)
      BC113256
      UniProtKB/Swiss-Prot
      Q2HJ84
      UniProtKB/TrEMBL
      Q0V8K8
      Related
      ENSBTAP00070042334.1, ENSBTAT00070069516.1
      Conserved Domains (2) summary
      pfam05920
      Location:277 → 316
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:80 → 165
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      143160275..143204710
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024990140.2 → XP_024845908.1  homeobox protein PKNOX1 isoform X1

      UniProtKB/Swiss-Prot
      Q2HJ84
      UniProtKB/TrEMBL
      Q0V8K8
      Conserved Domains (2) summary
      pfam05920
      Location:277 → 316
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:80 → 165
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    2. XM_024990142.2 → XP_024845910.1  homeobox protein PKNOX1 isoform X1

      UniProtKB/Swiss-Prot
      Q2HJ84
      UniProtKB/TrEMBL
      Q0V8K8
      Conserved Domains (2) summary
      pfam05920
      Location:277 → 316
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:80 → 165
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    3. XM_024990146.2 → XP_024845914.1  homeobox protein PKNOX1 isoform X2

      UniProtKB/TrEMBL
      Q0V8K8
      Conserved Domains (2) summary
      pfam05920
      Location:276 → 315
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:80 → 165
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    4. XM_059885187.1 → XP_059741170.1  homeobox protein PKNOX1 isoform X1

      UniProtKB/Swiss-Prot
      Q2HJ84
      UniProtKB/TrEMBL
      Q0V8K8
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2HJ84.1 GenPept UniProtKB/Swiss-Prot:Q2HJ84

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials