ETS2 ETS proto-oncogene 2, transcription factor [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: ETS2provided by VGNC
Official Full Name: ETS proto-oncogene 2, transcription factorprovided by VGNC
Primary source: VGNC:VGNC:28627
See related: EnsemblRapid:ENSBTAG00070027406
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	1	NC_037328.1 (151162151..151181633)

Chromosome 1 - NC_037328.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

DLX3 has a central role in controlling IFNT gene expression by associating with ETS2 on the IFNT promoter.
Title: The role of homeobox protein distal-less 3 and its interaction with ETS2 in regulating bovine interferon-tau gene expression-synergistic transcriptional activation with ETS2.

Submit: New GeneRIF Correction

General gene information

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Markers

ETV2 (e-PCR)
- UniSTS:266755

ETS2 (e-PCR)
- UniSTS:279357

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein C-ets-2

Names: avian erythroblastosis virus E26 (v-ets) oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080214.1 → NP_001073683.1 protein C-ets-2

See identical proteins and their annotated locations for NP_001073683.1

Status: PROVISIONAL

Source sequence(s)

BC126692

UniProtKB/Swiss-Prot

A1A4L6

UniProtKB/TrEMBL

A0AAF7AP20

Related

ENSBTAP00070037200.1, ENSBTAT00070062326.1

Conserved Domains (2) summary

cd08543
Location:85 → 173

SAM_PNT-ETS-2; Sterile alpha motif (SAM)/Pointed domain of ETS-2

smart00413
Location:363 → 447

ETS; erythroblast transformation specific domain