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    PPP1R12C protein phosphatase 1 regulatory subunit 12C [ Bos taurus (domestic cattle) ]

    Gene ID: 512431, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PPP1R12Cprovided by VGNC
    Official Full Name
    protein phosphatase 1 regulatory subunit 12Cprovided by VGNC
    Primary source
    VGNC:VGNC:52229
    See related
    BGD:BT14854; Ensembl:ENSBTAG00000017847
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PPP1R12C in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (62291297..62310501)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene troponin I3, cardiac type Neighboring gene troponin T1, slow skeletal type Neighboring gene uncharacterized LOC112442387 Neighboring gene EPS8 like 1 Neighboring gene retinol dehydrogenase 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables enzyme inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase 1 regulatory subunit 12C
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 12C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      62291297..62310501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024979381.2 → XP_024835149.1  protein phosphatase 1 regulatory subunit 12C isoform X1

      Conserved Domains (6) summary
      cd00204
      Location:95 → 279
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:100 → 131
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:57 → 131
      Ank_2; Ankyrin repeats (3 copies)
      pfam15898
      Location:683 → 784
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      cl26073
      Location:113 → 225
      Ank_2; Ankyrin repeats (3 copies)
      cl28033
      Location:320 → 700
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    2. XM_024979383.2 → XP_024835151.1  protein phosphatase 1 regulatory subunit 12C isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LWP2
      Related
      ENSBTAP00000065121.2, ENSBTAT00000077989.2
      Conserved Domains (6) summary
      cd00204
      Location:95 → 279
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:100 → 131
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:57 → 131
      Ank_2; Ankyrin repeats (3 copies)
      pfam15898
      Location:683 → 781
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      cl26073
      Location:113 → 225
      Ank_2; Ankyrin repeats (3 copies)
      cl28033
      Location:320 → 700
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    3. XM_024979382.2 → XP_024835150.1  protein phosphatase 1 regulatory subunit 12C isoform X2

      Conserved Domains (7) summary
      cd00204
      Location:95 → 279
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:100 → 131
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:57 → 131
      Ank_2; Ankyrin repeats (3 copies)
      pfam15898
      Location:682 → 783
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      cl26073
      Location:113 → 225
      Ank_2; Ankyrin repeats (3 copies)
      cl26386
      Location:409 → 631
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28310
      Location:538 → 668
      Rho; Transcription termination factor Rho [Transcription]

    4. XM_024979384.2 → XP_024835152.1  protein phosphatase 1 regulatory subunit 12C isoform X4

      Conserved Domains (7) summary
      cd00204
      Location:95 → 279
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:100 → 131
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:57 → 131
      Ank_2; Ankyrin repeats (3 copies)
      pfam15898
      Location:682 → 780
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      cl26073
      Location:113 → 225
      Ank_2; Ankyrin repeats (3 copies)
      cl26386
      Location:409 → 631
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
      cl28310
      Location:538 → 668
      Rho; Transcription termination factor Rho [Transcription]

    5. XM_024979385.2 → XP_024835153.1  protein phosphatase 1 regulatory subunit 12C isoform X5

      Conserved Domains (7) summary
      cd00204
      Location:95 → 279
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:100 → 131
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:57 → 131
      Ank_2; Ankyrin repeats (3 copies)
      pfam15898
      Location:665 → 766
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      cl25751
      Location:432 → 595
      DUF4045; Domain of unknown function (DUF4045)
      cl26073
      Location:113 → 225
      Ank_2; Ankyrin repeats (3 copies)
      cl28033
      Location:320 → 648
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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