U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ZP3 zona pellucida glycoprotein 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 280964, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    ZP3
    Gene description
    zona pellucida glycoprotein 3
    See related
    BGD:BT10636; Ensembl:ENSBTAG00000014834
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    Zp-3; Zp-3B
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ZP3 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (34446154..34453895)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene scavenger receptor cysteine rich family member with 4 domains Neighboring gene deltex E3 ubiquitin ligase 2 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene uroplakin 3B

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Evolutionary patterns of two major reproduction candidate genes (Zp2 and Zp3) reveal no contribution to reproductive isolation between bovine species. Chen S, et al. BMC Evol Biol, 2011 Jan 25. PMID 21266067, Free PMC Article
    2. Recombinant bovine zona pellucida glycoproteins ZP3 and ZP4 coexpressed in Sf9 cells form a sperm-binding active hetero-complex. Kanai S, et al. FEBS J, 2007 Oct. PMID 17894824
    3. Cloning and characterization of zona pellucida genes and cDNAs from a variety of mammalian species: the ZPA, ZPB and ZPC gene families. Harris JD, et al. DNA Seq, 1994. PMID 7841460
    4. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    5. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Polymorphism of Zp2 and the Zp3 did not show any contribution to reproductive isolation between the bovine species.
      Title: Evolutionary patterns of two major reproduction candidate genes (Zp2 and Zp3) reveal no contribution to reproductive isolation between bovine species.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    zona pellucida sperm-binding protein 3
    Names
    sperm receptor
    zona pellucida glycoprotein 3 preproprotein
    zona pellucida glycoprotein 3B
    zona pellucida glycoprotein ZP3B
    zona pellucida protein C

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173974.3 → NP_776399.2  zona pellucida sperm-binding protein 3 precursor

      See identical proteins and their annotated locations for NP_776399.2

      Status: VALIDATED

      Source sequence(s)
      BC146035, DAAA02058207
      UniProtKB/Swiss-Prot
      P48830
      UniProtKB/TrEMBL
      A6H6X7
      Related
      ENSBTAP00000019756.5, ENSBTAT00000019756.7
      Conserved Domains (2) summary
      smart00241
      Location:44 → 302
      ZP; Zona pellucida (ZP) domain
      pfam00100
      Location:187 → 300
      Zona_pellucida; Zona pellucida-like domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      34446154..34453895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48830.1 GenPept UniProtKB/Swiss-Prot:P48830

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.