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    ALDH1A1 aldehyde dehydrogenase 1 family member A1 [ Bos taurus (domestic cattle) ]

    Gene ID: 281615, updated on 30-Jan-2025

    Summary

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    Official Symbol
    ALDH1A1provided by VGNC
    Official Full Name
    aldehyde dehydrogenase 1 family member A1provided by VGNC
    Primary source
    VGNC:VGNC:25808
    See related
    BGD:BT16383; EnsemblRapid:ENSBTAG00070004174
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    ALDH1
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human all
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    Genomic context

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    See ALDH1A1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (49053228..49106706, complement)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1-alpha 1-like Neighboring gene transmembrane channel like 1 Neighboring gene uncharacterized LOC785403 Neighboring gene annexin A1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. ALDH1A1 effect on Yan Yellow Cattle preadipocyte differentiation. Hu Z, et al. Anim Biotechnol, 2021 Apr. PMID 31646946
    2. Characterization and localization of an aldehyde dehydrogenase to amacrine cells of bovine retina. Saari JC, et al. Vis Neurosci, 1995 Mar-Apr. PMID 7786847
    3. Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases. Beretta M, et al. J Biol Chem, 2008 Jun 27. PMID 18450747, Free PMC Article
    4. Crystal structure of eta-crystallin: adaptation of a class 1 aldehyde dehydrogenase for a new role in the eye lens. Bateman OA, et al. Biochemistry, 2003 Apr 22. PMID 12693930
    5. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ALDH1A1 effect on Yan Yellow Cattle preadipocyte differentiation.
      Title: ALDH1A1 effect on Yan Yellow Cattle preadipocyte differentiation.
    2. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 and ALDH2
      Title: Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128391

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables benzaldehyde dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aldehyde dehydrogenase 1A1
    Names
    3-deoxyglucosone dehydrogenase
    ALDH-E1
    ALHDII
    RALDH 1
    aldehyde dehydrogenase 1, soluble
    aldehyde dehydrogenase family 1 member A1
    aldehyde dehydrogenase, cytosolic
    ralDH1
    retinal dehydrogenase 1
    NP_776664.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174239.2 → NP_776664.1  aldehyde dehydrogenase 1A1

      See identical proteins and their annotated locations for NP_776664.1

      Status: PROVISIONAL

      Source sequence(s)
      L36128
      UniProtKB/Swiss-Prot
      P48644
      Related
      ENSBTAP00070005331.1, ENSBTAT00070009467.1
      Conserved Domains (2) summary
      cd07141
      Location:15 → 495
      ALDH_F1AB_F2_RALDH1; NAD+-dependent retinal dehydrogenase 1, ALDH families 1A, 1B, and 2-like
      PLN02466
      Location:3 → 492
      PLN02466; aldehyde dehydrogenase family 2 member

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      49053228..49106706 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48644.3 GenPept UniProtKB/Swiss-Prot:P48644

    Gene LinkOut

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