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    F3 coagulation factor III, tissue factor [ Bos taurus (domestic cattle) ]

    Gene ID: 280686, updated on 1-Jan-2025

    Summary

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    Official Symbol
    F3provided by VGNC
    Official Full Name
    coagulation factor III, tissue factorprovided by VGNC
    Primary source
    VGNC:VGNC:28687
    See related
    BGD:BT23303; Ensembl:ENSBTAG00000007101
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TF
    Annotation information
    Note: GeneIDs 280686 and 100849695 are annotated independently on Btau_4.6.1, but may be redundant loci. [17 Jun 2014]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (48954585..48965468)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112445986 Neighboring gene uncharacterized LOC132344873 Neighboring gene U6 spliceosomal RNA Neighboring gene ATP binding cassette subfamily D member 3 Neighboring gene uncharacterized LOC132344875 Neighboring gene uncharacterized LOC132344874

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. cDNA and amino acid sequences of bovine tissue factor. Takayenoki Y, et al. Biochem Biophys Res Commun, 1991 Dec 31. PMID 1764065
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tissue factor
    Names
    coagulation factor III (thromboplastin, tissue factor)
    thromboplastin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173878.2 → NP_776303.1  tissue factor precursor

      See identical proteins and their annotated locations for NP_776303.1

      Status: PROVISIONAL

      Source sequence(s)
      S74147
      UniProtKB/Swiss-Prot
      P30931, Q08DD5
      UniProtKB/TrEMBL
      A0AAA9TR18
      Related
      ENSBTAP00000009341.3, ENSBTAT00000009341.5
      Conserved Domains (2) summary
      pfam01108
      Location:33 → 118
      Tissue_fac; Tissue factor
      pfam09294
      Location:135 → 242
      Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      48954585..48965468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P30931.1 GenPept UniProtKB/Swiss-Prot:P30931

    Gene LinkOut

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