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    COL11A1 collagen type XI alpha 1 chain [ Bos taurus (domestic cattle) ]

    Gene ID: 287013, updated on 29-Jan-2025

    Summary

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    Official Symbol
    COL11A1provided by VGNC
    Official Full Name
    collagen type XI alpha 1 chainprovided by VGNC
    Primary source
    VGNC:VGNC:50080
    See related
    BGD:BT10433; Ensembl:ENSBTAG00000021217
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See COL11A1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    68
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (40304545..40530671)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132344991 Neighboring gene radial spoke head protein 9 homolog Neighboring gene superoxide dismutase [Mn], mitochondrial-like Neighboring gene large ribosomal subunit protein uL30-like Neighboring gene integrin beta-1-binding protein 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of the chains of type V/type XI collagen present in bovine vitreous. Mayne R, et al. J Biol Chem, 1993 May 5. PMID 8486632
    2. Concerted modulation of alpha 1(XI) and alpha 2(V) collagen mRNAs in bovine vascular smooth muscle cells. Brown KE, et al. J Biol Chem, 1991 Dec 5. PMID 1744123
    3. Structural analysis of cross-linking domains in cartilage type XI collagen. Insights on polymeric assembly. Wu JJ, et al. J Biol Chem, 1995 Aug 11. PMID 7642541
    4. The collagen family members as cell adhesion proteins. Heino J. Bioessays, 2007 Oct. PMID 17876790
    5. Establishment of a high throughput EST sequencing system using poly(A) tail-removed cDNA libraries and determination of 36,000 bovine ESTs. Takasuga A, et al. Nucleic Acids Res, 2001 Nov 15. PMID 11713328, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent conferring tensile strength IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of collagen type XI trimer IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    collagen alpha-1(XI) chain
    Names
    collagen, type XI, alpha 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166509.2 → NP_001159981.2  collagen alpha-1(XI) chain

      Status: VALIDATED

      Source sequence(s)
      AV594460, AV595342, DAAA02007697, DAAA02007700, DAAA02007702, DAAA02007703, DAAA02007705, DAAA02007707
      UniProtKB/TrEMBL
      F1N0K0
      Related
      ENSBTAP00070018709.1, ENSBTAT00070031724.1
      Conserved Domains (3) summary
      pfam01391
      Location:852 → 911
      Collagen; Collagen triple helix repeat (20 copies)
      smart00210
      Location:38 → 229
      TSPN; Thrombospondin N-terminal -like domains
      pfam01410
      Location:1589 → 1815
      COLFI; Fibrillar collagen C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      40304545..40530671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024985040.2 → XP_024840808.1  collagen alpha-1(XI) chain isoform X1

      UniProtKB/TrEMBL
      A0AAA9RZ18, A0AAA9SUH9
      Related
      ENSBTAP00070018718.1, ENSBTAT00070031746.1
      Conserved Domains (3) summary
      pfam01391
      Location:840 → 899
      Collagen; Collagen triple helix repeat (20 copies)
      smart00210
      Location:38 → 229
      TSPN; Thrombospondin N-terminal -like domains
      pfam01410
      Location:1577 → 1803
      COLFI; Fibrillar collagen C-terminal domain

    2. XM_059881885.1 → XP_059737868.1  collagen alpha-1(XI) chain isoform X3

      UniProtKB/TrEMBL
      A0AAA9T2Z4
      Related
      ENSBTAP00070018752.1, ENSBTAT00070031860.1

    3. XM_059881882.1 → XP_059737865.1  collagen alpha-1(XI) chain isoform X2

      UniProtKB/TrEMBL
      A0AAA9SD09, F1N0K0
      Related
      ENSBTAP00070018741.1, ENSBTAT00070031830.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28083.1 GenPept UniProtKB/Swiss-Prot:Q28083

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.