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    WDR75 WD repeat domain 75 [ Bos taurus (domestic cattle) ]

    Gene ID: 521240, updated on 30-Jan-2025

    Summary

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    Official Symbol
    WDR75provided by VGNC
    Official Full Name
    WD repeat domain 75provided by VGNC
    Primary source
    VGNC:VGNC:36919
    See related
    BGD:BT28924; EnsemblRapid:ENSBTAG00070002187
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See WDR75 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (6935085..6976936, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100848294 Neighboring gene lysine-specific demethylase 3A-like Neighboring gene uncharacterized LOC101905730 Neighboring gene uncharacterized LOC132342939 Neighboring gene collagen alpha-2(V) chain-like Neighboring gene microRNA mir-2917

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC152586

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    WD repeat-containing protein 75

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102062.2 → NP_001095532.1  WD repeat-containing protein 75

      See identical proteins and their annotated locations for NP_001095532.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149959
      UniProtKB/TrEMBL
      A6QQR0, F1MCR2
      Related
      ENSBTAP00070002804.1, ENSBTAT00070005002.1
      Conserved Domains (3) summary
      COG2319
      Location:24 → 320
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:61 → 110
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:20 → 314
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      6935085..6976936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202201.5 → XP_005202258.1  WD repeat-containing protein 75 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MDP7, F1MCR2
      Related
      ENSBTAP00070002807.1, ENSBTAT00070005005.1
      Conserved Domains (3) summary
      COG2319
      Location:51 → 345
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:86 → 124
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:51 → 339
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein Strain
    Heading Accession and Version

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