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    NHEJ1 non-homologous end joining factor 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 509157, updated on 27-Dec-2024

    Summary

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    Official Symbol
    NHEJ1provided by VGNC
    Official Full Name
    non-homologous end joining factor 1provided by VGNC
    Primary source
    VGNC:VGNC:32064
    See related
    BGD:BT25745; Ensembl:ENSBTAG00000031041
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See NHEJ1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (107020701..107112900, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 65 Neighboring gene Indian hedgehog signaling molecule Neighboring gene solute carrier family 23 member 3 Neighboring gene cyclin Pas1/PHO80 domain containing 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC139115

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA end binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via nonhomologous end joining IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA ligase IV complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    non-homologous end-joining factor 1
    Names
    nonhomologous end-joining factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075393.1 → NP_001068861.1  non-homologous end-joining factor 1

      Status: PROVISIONAL

      Source sequence(s)
      BC116103
      UniProtKB/TrEMBL
      A0AAA9SB29, F6RWI0, Q1JQA6
      Related
      ENSBTAP00000083301.1, ENSBTAT00000114836.1
      Conserved Domains (1) summary
      pfam09302
      Location:12 → 174
      XLF; XLF-Cernunnos, XRcc4-like factor, NHEJ component

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      107020701..107112900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015459118.3 → XP_015314604.2  non-homologous end-joining factor 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SB29, F6RWI0
      Conserved Domains (1) summary
      pfam09302
      Location:12 → 152
      XLF; XLF-Cernunnos, XRcc4-like factor, NHEJ component
    Nucleotide Protein Strain
    Heading Accession and Version

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