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    PTP4A3 protein tyrosine phosphatase 4A3 [ Bos taurus (domestic cattle) ]

    Gene ID: 100137722, updated on 1-Jan-2025

    Summary

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    Official Symbol
    PTP4A3provided by VGNC
    Official Full Name
    protein tyrosine phosphatase 4A3provided by VGNC
    Primary source
    VGNC:VGNC:33525
    See related
    Ensembl:ENSBTAG00000046467
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PTP4A3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (2553480..2585776, complement)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene chromosome 14 C8orf90 homolog Neighboring gene uncharacterized LOC132342170 Neighboring gene maestro heat-like repeat family member 5 Neighboring gene G protein-coupled receptor 20 Neighboring gene uncharacterized LOC112449594 Neighboring gene solute carrier family 45 member 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC155222

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endothelial cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein tyrosine phosphatase type IVA 3
    Names
    protein tyrosine phosphatase type IVA, member 3
    NP_001077235.1
    XP_005215180.1
    XP_005215181.1
    XP_010810118.1
    XP_015329814.1
    XP_024857165.1
    XP_024857166.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083766.1 → NP_001077235.1  protein tyrosine phosphatase type IVA 3

      See identical proteins and their annotated locations for NP_001077235.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133386
      UniProtKB/Swiss-Prot
      A2VDT1
      UniProtKB/TrEMBL
      A0AAF6ZRY7
      Related
      ENSBTAP00000056281.1, ENSBTAT00000064455.3
      Conserved Domains (1) summary
      cl28904
      Location:5 → 158
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      2553480..2585776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025001398.2 → XP_024857166.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      A2VDT1
      UniProtKB/TrEMBL
      A0AAF6ZRY7
      Conserved Domains (1) summary
      cl28904
      Location:5 → 158
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    2. XM_015474328.2 → XP_015329814.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      A2VDT1
      UniProtKB/TrEMBL
      A0AAF6ZRY7
      Conserved Domains (1) summary
      cl28904
      Location:5 → 158
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    3. XM_005215124.5 → XP_005215181.1  protein tyrosine phosphatase type IVA 3 isoform X1

      See identical proteins and their annotated locations for XP_005215181.1

      UniProtKB/Swiss-Prot
      A2VDT1
      UniProtKB/TrEMBL
      A0AAF6ZRY7
      Conserved Domains (1) summary
      cl28904
      Location:5 → 158
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    4. XM_025001397.2 → XP_024857165.1  protein tyrosine phosphatase type IVA 3 isoform X1

      UniProtKB/Swiss-Prot
      A2VDT1
      UniProtKB/TrEMBL
      A0AAF6ZRY7
      Conserved Domains (1) summary
      cl28904
      Location:5 → 158
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    5. XM_005215123.5 → XP_005215180.1  protein tyrosine phosphatase type IVA 3 isoform X1

      See identical proteins and their annotated locations for XP_005215180.1

      UniProtKB/Swiss-Prot
      A2VDT1
      UniProtKB/TrEMBL
      A0AAF6ZRY7
      Conserved Domains (1) summary
      cl28904
      Location:5 → 158
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    6. XM_010811816.4 → XP_010810118.1  protein tyrosine phosphatase type IVA 3 isoform X1

      See identical proteins and their annotated locations for XP_010810118.1

      UniProtKB/Swiss-Prot
      A2VDT1
      UniProtKB/TrEMBL
      A0AAF6ZRY7
      Conserved Domains (1) summary
      cl28904
      Location:5 → 158
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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