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    FBXL12 F-box and leucine rich repeat protein 12 [ Bos taurus (domestic cattle) ]

    Gene ID: 617304, updated on 1-Jan-2025

    Summary

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    Official Symbol
    FBXL12provided by VGNC
    Official Full Name
    F-box and leucine rich repeat protein 12provided by VGNC
    Primary source
    VGNC:VGNC:52772
    See related
    BGD:BT28574; Ensembl:ENSBTAG00000025148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See FBXL12 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (14408570..14415316, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 26 Neighboring gene olfactory receptor family 7 subfamily D member 15, pseudogene Neighboring gene zinc finger protein 266 Neighboring gene ubiquitin like 5 Neighboring gene peptidylprolyl cis/trans isomerase, NIMA-interacting 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC128704

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box/LRR-repeat protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040600.2 → NP_001035690.1  F-box/LRR-repeat protein 12

      See identical proteins and their annotated locations for NP_001035690.1

      Status: PROVISIONAL

      Source sequence(s)
      BC108120
      UniProtKB/Swiss-Prot
      Q32PG9
      Related
      ENSBTAP00000035085.4, ENSBTAT00000035207.5
      Conserved Domains (2) summary
      sd00034
      Location:44 → 70
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 48
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14408570..14415316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024994625.2 → XP_024850393.1  F-box/LRR-repeat protein 12 isoform X2

      Conserved Domains (1) summary
      sd00034
      Location:51 → 72
      LRR_AMN1; leucine-rich repeat [structural motif]

    2. XM_015465621.3 → XP_015321107.2  F-box/LRR-repeat protein 12 isoform X2

      Conserved Domains (1) summary
      sd00034
      Location:51 → 72
      LRR_AMN1; leucine-rich repeat [structural motif]

    3. XM_059888401.1 → XP_059744384.1  F-box/LRR-repeat protein 12 isoform X2

    4. XM_010800700.4 → XP_010799002.2  F-box/LRR-repeat protein 12 isoform X1

      Conserved Domains (2) summary
      sd00034
      Location:83 → 104
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl28166
      Location:92 → 205
      AMN1; Antagonist of mitotic exit network protein 1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32PG9.1 GenPept UniProtKB/Swiss-Prot:Q32PG9

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