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    SYTL2 synaptotagmin like 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 614406, updated on 30-Jan-2025

    Summary

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    Gene symbol
    SYTL2
    Gene description
    synaptotagmin like 2
    See related
    BGD:BT28515; EnsemblRapid:ENSBTAG00070033288
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SYTL2 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (9741747..9862429)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol binding clathrin assembly protein Neighboring gene coiled-coil domain containing 83 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene coiled-coil domain containing 89 Neighboring gene CREB/ATF bZIP transcription factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC151530

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables neurexin family protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in exocytic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    synaptotagmin-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102278.2 → NP_001095748.2  synaptotagmin-like protein 2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000029
      UniProtKB/Swiss-Prot
      A6QP06
      Related
      ENSBTAP00070045987.1, ENSBTAT00070075357.1
      Conserved Domains (4) summary
      PHA03255
      Location:405 → 486
      PHA03255; BDLF3; Provisional
      cd04020
      Location:778 → 934
      C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
      cl14603
      Location:638 → 765
      C2; C2 domain
      cl22851
      Location:5 → 41
      PHD_SF; PHD finger superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      9741747..9862429
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059883024.1 → XP_059739007.1  synaptotagmin-like protein 2 isoform X1

    2. XM_059883025.1 → XP_059739008.1  synaptotagmin-like protein 2 isoform X1

    3. XM_059883023.1 → XP_059739006.1  synaptotagmin-like protein 2 isoform X1

    4. XM_024987316.2 → XP_024843084.2  synaptotagmin-like protein 2 isoform X5

    5. XM_059883027.1 → XP_059739010.1  synaptotagmin-like protein 2 isoform X3

    6. XM_059883028.1 → XP_059739011.1  synaptotagmin-like protein 2 isoform X6

      UniProtKB/Swiss-Prot
      A6QP06

    7. XM_059883026.1 → XP_059739009.1  synaptotagmin-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SA75
      Related
      ENSBTAP00070046001.1, ENSBTAT00070075375.1

    8. XM_010820814.4 → XP_010819116.2  synaptotagmin-like protein 2 isoform X4

      UniProtKB/TrEMBL
      A0AAA9SUT7
      Related
      ENSBTAP00070045917.1, ENSBTAT00070075271.1
      Conserved Domains (3) summary
      cd04020
      Location:1555 → 1711
      C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
      cd08393
      Location:1415 → 1542
      C2A_SLP-1_2; C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2
      cl22851
      Location:5 → 41
      PHD_SF; PHD finger superfamily

    9. XM_005226687.5 → XP_005226744.2  synaptotagmin-like protein 2 isoform X8

      UniProtKB/Swiss-Prot
      A6QP06
      UniProtKB/TrEMBL
      A0AAA9SJB3
      Related
      ENSBTAP00070045965.1, ENSBTAT00070075333.1
      Conserved Domains (4) summary
      cd04020
      Location:738 → 894
      C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
      cl14603
      Location:598 → 725
      C2; C2 domain
      cl22851
      Location:5 → 41
      PHD_SF; PHD finger superfamily
      cl25495
      Location:405 → 486
      Endomucin

    10. XM_005226685.5 → XP_005226742.2  synaptotagmin-like protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A3Q1N0D1
      Conserved Domains (4) summary
      cd04020
      Location:762 → 918
      C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
      cl14603
      Location:622 → 749
      C2; C2 domain
      cl22851
      Location:5 → 41
      PHD_SF; PHD finger superfamily
      cl25495
      Location:405 → 486
      Endomucin

    11. XM_015461117.3 → XP_015316603.2  synaptotagmin-like protein 2 isoform X9

      UniProtKB/TrEMBL
      A0AAA9T1I8
      Related
      ENSBTAP00070045850.1, ENSBTAT00070075180.1
      Conserved Domains (2) summary
      cd04020
      Location:200 → 356
      C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
      cl14603
      Location:60 → 187
      C2; C2 domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6QP06.1 GenPept UniProtKB/Swiss-Prot:A6QP06

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