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    RWDD3 RWD domain containing 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 614557, updated on 27-Dec-2024

    Summary

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    Official Symbol
    RWDD3provided by VGNC
    Official Full Name
    RWD domain containing 3provided by VGNC
    Primary source
    VGNC:VGNC:34228
    See related
    BGD:BT13027; Ensembl:ENSBTAG00000021537
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RWDD3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (48239810..48252379, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132344997 Neighboring gene uncharacterized LOC132344872 Neighboring gene uncharacterized LOC112445985 Neighboring gene TLC domain containing 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of hypoxia-inducible factor-1alpha signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein sumoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RWD domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098128.1 → NP_001091597.1  RWD domain-containing protein 3

      See identical proteins and their annotated locations for NP_001091597.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133512
      UniProtKB/Swiss-Prot
      A3KN24
      UniProtKB/TrEMBL
      A0AAF6Z9Q2
      Related
      ENSBTAP00000028701.5, ENSBTAT00000028701.6
      Conserved Domains (1) summary
      pfam05773
      Location:1 → 111
      RWD; RWD domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      48239810..48252379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010803325.4 → XP_010801627.1  RWD domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A0AAF6Z9Q2
      Conserved Domains (1) summary
      smart00591
      Location:1 → 70
      RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain

    2. XM_010803326.4 → XP_010801628.1  RWD domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      A0AAA9S2R0
      Conserved Domains (1) summary
      pfam05773
      Location:1 → 111
      RWD; RWD domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A3KN24.1 GenPept UniProtKB/Swiss-Prot:A3KN24

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