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    CD2AP CD2 associated protein [ Bos taurus (domestic cattle) ]

    Gene ID: 533188, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CD2APprovided by VGNC
    Official Full Name
    CD2 associated proteinprovided by VGNC
    Primary source
    VGNC:VGNC:27022
    See related
    BGD:BT15353; Ensembl:ENSBTAG00000000322
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CD2AP in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (20603046..20689497)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase A Neighboring gene TNF receptor superfamily member 21 Neighboring gene adhesion G protein-coupled receptor F2 Neighboring gene adhesion G protein-coupled receptor F4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Identification and characterisation of a Theileria annulata proline-rich microtubule and SH3 domain-interacting protein (TaMISHIP) that forms a complex with CLASP1, EB1, and CD2AP at the schizont surface. Huber S, et al. Cell Microbiol, 2018 Jul. PMID 29520916, Free PMC Article
    2. Comparative analysis of 82 expressed sequence tags from a cattle ovary cDNA library. Ma RZ, et al. Mamm Genome, 1998 Jul. PMID 9657852
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell leading edge IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CD2-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206539.1 → NP_001193468.1  CD2-associated protein

      Status: VALIDATED

      Source sequence(s)
      BC102654, BF041363, CB223313, CK978169, DV777483, DY057953, EE349434, EE940257, EV637869, EV788906
      UniProtKB/TrEMBL
      Q3ZCA4
      Related
      ENSBTAP00000063832.1, ENSBTAT00000073351.1
      Conserved Domains (3) summary
      cd12053
      Location:3 → 58
      SH3_CD2AP_1; First Src Homology 3 domain (SH3A) of CD2-associated protein
      cd12054
      Location:111 → 165
      SH3_CD2AP_2; Second Src Homology 3 domain (SH3B) of CD2-associated protein
      cd12056
      Location:271 → 327
      SH3_CD2AP_3; Third Src Homology 3 domain (SH3C) of CD2-associated protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      20603046..20689497
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010818207.4 → XP_010816509.1  CD2-associated protein isoform X2

      Conserved Domains (2) summary
      cd12053
      Location:3 → 58
      SH3_CD2AP_1; First Src Homology 3 domain (SH3A) of CD2-associated protein
      cd12056
      Location:198 → 254
      SH3_CD2AP_3; Third Src Homology 3 domain (SH3C) of CD2-associated protein

    2. XM_015459806.3 → XP_015315292.1  CD2-associated protein isoform X1

      UniProtKB/TrEMBL
      F1MM14
      Related
      ENSBTAP00000053206.4, ENSBTAT00000061046.4
      Conserved Domains (2) summary
      cd12054
      Location:67 → 121
      SH3_CD2AP_2; Second Src Homology 3 domain (SH3B) of CD2-associated protein
      cd12056
      Location:227 → 283
      SH3_CD2AP_3; Third Src Homology 3 domain (SH3C) of CD2-associated protein
    Nucleotide Protein Strain
    Heading Accession and Version

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