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    SRPK2 SRSF protein kinase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 505945, updated on 1-Jan-2025

    Summary

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    Official Symbol
    SRPK2provided by VGNC
    Official Full Name
    SRSF protein kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:35289
    See related
    BGD:BT26276; Ensembl:ENSBTAG00000002175
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SRPK2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (46293929..46541402, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene LHFPL tetraspan subfamily member 3 Neighboring gene uncharacterized LOC132345184 Neighboring gene lysine methyltransferase 2E (inactive) Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene V-type proton ATPase subunit e 1-like Neighboring gene large ribosomal subunit protein uL23-like Neighboring gene PRELI domain containing protein 3B-like Neighboring gene pseudouridine synthase 7 Neighboring gene EF-hand calcium binding domain 10 Neighboring gene RAD50 interactor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in spliceosomal complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase SRPK2; SRSF protein kinase 2
    Names
    SFRS protein kinase 2
    XP_010802486.2
    XP_024846804.1
    XP_024846805.1
    XP_024846807.1
    XP_024846808.1
    XP_024846810.1
    XP_024846814.1
    XP_059741822.1
    XP_059741823.1
    XP_059741824.1
    XP_059741825.1
    XP_059741827.1
    XP_059741828.1
    XP_059741829.1
    XP_059741830.1
    XP_059741831.1
    XP_059741832.1
    XP_059741833.1
    XP_059741834.1
    XP_059741835.1
    XP_059741837.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46293929..46541402 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991039.2 → XP_024846807.1  SRSF protein kinase 2 isoform X9

      UniProtKB/TrEMBL
      A0A3Q1NBC4
      Conserved Domains (2) summary
      cl21453
      Location:82 → 270
      PKc_like; Protein Kinases, catalytic domain
      cl27511
      Location:324 → 397
      Na_Ca_ex; Sodium/calcium exchanger protein

    2. XM_059885841.1 → XP_059741824.1  SRSF protein kinase 2 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    3. XM_059885847.1 → XP_059741830.1  SRSF protein kinase 2 isoform X13

      UniProtKB/TrEMBL
      A0A3Q1NBC4
      Related
      ENSBTAP00000068620.2, ENSBTAT00000074952.2

    4. XM_059885849.1 → XP_059741832.1  SRSF protein kinase 2 isoform X13

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    5. XM_024991037.2 → XP_024846805.1  SRSF protein kinase 2 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1NBC4
      Conserved Domains (3) summary
      cd14217
      Location:114 → 302
      STKc_SRPK2; Catalytic domain of the Serine/Threonine Kinase, Serine-aRginine Protein Kinase 2
      cl21453
      Location:552 → 732
      PKc_like; Protein Kinases, catalytic domain
      cl27511
      Location:356 → 429
      Na_Ca_ex; Sodium/calcium exchanger protein

    6. XM_024991036.2 → XP_024846804.1  SRSF protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MH41, A0A3Q1NBC4
      Related
      ENSBTAP00000073552.1, ENSBTAT00000075359.2
      Conserved Domains (3) summary
      cd14217
      Location:114 → 302
      STKc_SRPK2; Catalytic domain of the Serine/Threonine Kinase, Serine-aRginine Protein Kinase 2
      cl21453
      Location:552 → 763
      PKc_like; Protein Kinases, catalytic domain
      cl27511
      Location:356 → 429
      Na_Ca_ex; Sodium/calcium exchanger protein

    7. XM_059885846.1 → XP_059741829.1  SRSF protein kinase 2 isoform X11

      UniProtKB/TrEMBL
      A0A3Q1LKL2, A0A3Q1LWI0
      Related
      ENSBTAP00000057010.2, ENSBTAT00000085286.2

    8. XM_059885840.1 → XP_059741823.1  SRSF protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LWI0

    9. XM_059885850.1 → XP_059741833.1  SRSF protein kinase 2 isoform X15

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    10. XM_024991042.2 → XP_024846810.1  SRSF protein kinase 2 isoform X14

      UniProtKB/TrEMBL
      A0A3Q1NBC4
      Conserved Domains (2) summary
      cl21453
      Location:77 → 265
      PKc_like; Protein Kinases, catalytic domain
      cl27511
      Location:319 → 392
      Na_Ca_ex; Sodium/calcium exchanger protein

    11. XM_024991040.2 → XP_024846808.1  SRSF protein kinase 2 isoform X10

      UniProtKB/TrEMBL
      A0A3Q1NBC4, A0AAA9T546
      Related
      ENSBTAP00000091654.1, ENSBTAT00000124639.1
      Conserved Domains (2) summary
      cl21453
      Location:77 → 265
      PKc_like; Protein Kinases, catalytic domain
      cl27511
      Location:319 → 392
      Na_Ca_ex; Sodium/calcium exchanger protein

    12. XM_059885854.1 → XP_059741837.1  SRSF protein kinase 2 isoform X16

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    13. XM_059885848.1 → XP_059741831.1  SRSF protein kinase 2 isoform X13

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    14. XM_059885852.1 → XP_059741835.1  SRSF protein kinase 2 isoform X16

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    15. XM_059885845.1 → XP_059741828.1  SRSF protein kinase 2 isoform X7

      UniProtKB/TrEMBL
      A0A3Q1LWI0
      Related
      ENSBTAP00000061592.2, ENSBTAT00000077456.2

    16. XM_024991046.2 → XP_024846814.1  SRSF protein kinase 2 isoform X17

      UniProtKB/TrEMBL
      A0A3Q1NBC4
      Conserved Domains (2) summary
      cl21453
      Location:406 → 617
      PKc_like; Protein Kinases, catalytic domain
      cl27511
      Location:210 → 283
      Na_Ca_ex; Sodium/calcium exchanger protein

    17. XM_059885851.1 → XP_059741834.1  SRSF protein kinase 2 isoform X16

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    18. XM_010804184.4 → XP_010802486.2  SRSF protein kinase 2 isoform X12

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    19. XM_059885844.1 → XP_059741827.1  SRSF protein kinase 2 isoform X6

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    20. XM_059885842.1 → XP_059741825.1  SRSF protein kinase 2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    21. XM_059885839.1 → XP_059741822.1  SRSF protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1NBC4

    RNA

    1. XR_009494210.1 RNA Sequence

    2. XR_009494209.1 RNA Sequence

    3. XR_009494208.1 RNA Sequence

    4. XR_009494207.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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