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    FZD3 frizzled class receptor 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 445419, updated on 30-Jan-2025

    Summary

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    Official Symbol
    FZD3provided by VGNC
    Official Full Name
    frizzled class receptor 3provided by VGNC
    Primary source
    VGNC:VGNC:58460
    See related
    BGD:BT21320; EnsemblRapid:ENSBTAG00070015822
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See FZD3 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (10140657..10238540, complement)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 9 Neighboring gene transfer RNA arginine (anticodon GCG) Neighboring gene exostosin like glycosyltransferase 3 Neighboring gene F-box protein 16 Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger protein 395

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling. Goodwin AM, et al. Dev Dyn, 2006 Nov. PMID 17013885
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Wnt receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables Wnt-protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in non-canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    frizzled-3
    Names
    frizzled 3, seven transmembrane spanning receptor
    frizzled family receptor 3
    frizzled homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192964.3 → NP_001179893.2  frizzled-3 precursor

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000008
      UniProtKB/TrEMBL
      A0AAA9SUV5
      Related
      ENSBTAP00070020958.1, ENSBTAT00070035647.1
      Conserved Domains (2) summary
      cd07449
      Location:24 → 150
      CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
      cd15033
      Location:192 → 512
      7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      10140657..10238540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024995500.2 → XP_024851268.1  frizzled-3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SUV5, F1MLG5
      Related
      ENSBTAP00070020946.1, ENSBTAT00070035630.1
      Conserved Domains (2) summary
      cd07449
      Location:24 → 150
      CRD_FZ3; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 3 (Fz3) receptor
      cd15033
      Location:192 → 529
      7tmF_FZD3; class F frizzled subfamily 3, member of 7-transmembrane G protein-coupled receptors

    2. XM_059888971.1 → XP_059744954.1  frizzled-3 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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