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    SWAP70 switching B cell complex subunit SWAP70 [ Bos taurus (domestic cattle) ]

    Gene ID: 533720, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SWAP70provided by VGNC
    Official Full Name
    switching B cell complex subunit SWAP70provided by VGNC
    Primary source
    VGNC:VGNC:54893
    See related
    BGD:BT27717; Ensembl:ENSBTAG00000001987
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    HSPC321
    Orthologs
    human mouse all
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    Genomic context

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    See SWAP70 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (42918199..43062476, complement)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene SET binding factor 2 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene uncharacterized LOC104974249 Neighboring gene COMM domain-containing protein 8-like Neighboring gene uncharacterized LOC112441628 Neighboring gene WEE1 G2 checkpoint kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Shinohara M, et al. Nature, 2002 Apr 18. PMID 11961559
    2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    switch-associated protein 70
    Names
    SWAP switching B-cell complex 70kDa subunit
    SWAP switching B-cell complex subunit 70
    SWAP-70 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080297.2 → NP_001073766.2  switch-associated protein 70

      See identical proteins and their annotated locations for NP_001073766.2

      Status: PROVISIONAL

      Source sequence(s)
      BC146071
      UniProtKB/Swiss-Prot
      P0C1G6
      UniProtKB/TrEMBL
      A6H709
      Related
      ENSBTAP00000002578.4, ENSBTAT00000002578.5
      Conserved Domains (2) summary
      cd13273
      Location:204 → 313
      PH_SWAP-70; Switch-associated protein-70 Pleckstrin homology (PH) domain
      cl25732
      Location:332 → 549
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42918199..43062476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024975336.2 → XP_024831104.1  switch-associated protein 70 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M111, A0AAA9TF67
      Related
      ENSBTAP00000061706.1, ENSBTAT00000079754.2
      Conserved Domains (2) summary
      cd13273
      Location:185 → 294
      PH_SWAP-70; Switch-associated protein-70 Pleckstrin homology (PH) domain
      cl25732
      Location:313 → 530
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_010812481.4 → XP_010810783.1  switch-associated protein 70 isoform X2

      UniProtKB/Swiss-Prot
      P0C1G6
      UniProtKB/TrEMBL
      A0A3Q1MGB5
      Related
      ENSBTAP00000070218.1, ENSBTAT00000082705.2
      Conserved Domains (1) summary
      cl17171
      Location:215 → 264
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C1G6.1 GenPept UniProtKB/Swiss-Prot:P0C1G6

    Gene LinkOut

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