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    HMMR hyaluronan mediated motility receptor [ Bos taurus (domestic cattle) ]

    Gene ID: 281227, updated on 27-Dec-2024

    Summary

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    Official Symbol
    HMMRprovided by VGNC
    Official Full Name
    hyaluronan mediated motility receptorprovided by VGNC
    Primary source
    VGNC:VGNC:29884
    See related
    BGD:BT15961; Ensembl:ENSBTAG00000014773
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    rhamm
    Orthologs
    human mouse all
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    Genomic context

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    See HMMR in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (75136959..75170625)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene cyclin G1 Neighboring gene NudC domain containing 2 Neighboring gene methionine adenosyltransferase 2B Neighboring gene large ribosomal subunit protein eL30-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Expression of hyaluronan synthases and corresponding hyaluronan receptors is differentially regulated during oocyte maturation in cattle. Schoenfelder M, et al. Biol Reprod, 2003 Jul. PMID 12620932
    2. Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos. Stojkovic M, et al. Biol Reprod, 2003 Jan. PMID 12493696
    3. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin. Matou-Nasri S, et al. Int J Oncol, 2009 Oct. PMID 19724912
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin.
      Title: Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin.
    2. mRNA and protein expression in different stages of in vitro-produced embryos
      Title: Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hyaluronic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hyaluronan mediated motility receptor
    Names
    receptor for hyaluronic acid mediated motility

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206621.1 → NP_001193550.1  hyaluronan mediated motility receptor

      See identical proteins and their annotated locations for NP_001193550.1

      Status: VALIDATED

      Source sequence(s)
      AF499008, DV801952, EE340088, EH179791, NKLS02000007
      UniProtKB/TrEMBL
      A0A3Q1MJE8
      Related
      ENSBTAP00000071461.2, ENSBTAT00000080269.2
      Conserved Domains (3) summary
      pfam15905
      Location:16 → 339
      HMMR_N; Hyaluronan mediated motility receptor N-terminal
      pfam15908
      Location:553 → 709
      HMMR_C; Hyaluronan mediated motility receptor C-terminal
      cl25732
      Location:195 → 565
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      75136959..75170625
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005209695.5 → XP_005209752.1  hyaluronan mediated motility receptor isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MJE8, F1N331
      Related
      ENSBTAP00000019652.7, ENSBTAT00000019652.7
      Conserved Domains (3) summary
      pfam15905
      Location:16 → 340
      HMMR_N; Hyaluronan mediated motility receptor N-terminal
      pfam15908
      Location:554 → 710
      HMMR_C; Hyaluronan mediated motility receptor C-terminal
      cl25732
      Location:196 → 566
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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