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    ADAMDEC1 ADAM-like, decysin 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 505890, updated on 27-Dec-2024

    Summary

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    Gene symbol
    ADAMDEC1
    Gene description
    ADAM-like, decysin 1
    See related
    BGD:BT17773; Ensembl:ENSBTAG00000037929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

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    See ADAMDEC1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (71496938..71622274)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345974 Neighboring gene ras-related GTP-binding protein A Neighboring gene ADAM metallopeptidase domain 7 Neighboring gene neurofilament medium chain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ADAM DEC1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206371.1 → NP_001193300.1  ADAM DEC1 precursor

      Status: VALIDATED

      Source sequence(s)
      BC102756
      UniProtKB/TrEMBL
      Q3SZQ0
      Conserved Domains (4) summary
      cd04269
      Location:205 → 397
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:205 → 399
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:41 → 157
      Pep_M12B_propep; Reprolysin family propeptide
      cl10507
      Location:416 → 448
      Disintegrin; Disintegrin

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      71496938..71622274
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010808061.4 → XP_010806363.1  ADAM DEC1 isoform X4

      UniProtKB/TrEMBL
      A0AAA9SBA4, F1MSZ5
      Related
      ENSBTAP00000048880.3, ENSBTAT00000055272.4
      Conserved Domains (5) summary
      smart00050
      Location:418 → 492
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:495 → 622
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:205 → 399
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:205 → 401
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:42 → 156
      Pep_M12B_propep; Reprolysin family propeptide

    2. XM_005210280.5 → XP_005210337.2  ADAM DEC1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1M3P5, A0AAA9SBA4
      Related
      ENSBTAP00000068149.1, ENSBTAT00000072336.2
      Conserved Domains (4) summary
      smart00050
      Location:418 → 492
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:495 → 622
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:205 → 399
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01562
      Location:31 → 158
      Pep_M12B_propep; Reprolysin family propeptide

    3. XM_010808060.4 → XP_010806362.2  ADAM DEC1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SJC3
      Related
      ENSBTAP00000083908.1, ENSBTAT00000105641.1
      Conserved Domains (6) summary
      smart00050
      Location:418 → 492
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:495 → 622
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:205 → 399
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01562
      Location:31 → 158
      Pep_M12B_propep; Reprolysin family propeptide
      cl10507
      Location:1203 → 1235
      Disintegrin
      cl26139
      Location:992 → 1186
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease

    4. XM_005210279.5 → XP_005210336.2  ADAM DEC1 isoform X2

      UniProtKB/TrEMBL
      F1MJP4
      Related
      ENSBTAP00000001496.7, ENSBTAT00000001496.7
      Conserved Domains (6) summary
      smart00050
      Location:418 → 492
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:495 → 622
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:205 → 399
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01562
      Location:31 → 158
      Pep_M12B_propep; Reprolysin family propeptide
      cl10507
      Location:1182 → 1214
      Disintegrin
      cl26139
      Location:971 → 1165
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease

    RNA

    1. XR_001500869.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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