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    RBL2 RB transcriptional corepressor like 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 533294, updated on 30-Jan-2025

    Summary

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    Official Symbol
    RBL2provided by VGNC
    Official Full Name
    RB transcriptional corepressor like 2provided by VGNC
    Primary source
    VGNC:VGNC:33782
    See related
    BGD:BT11933; EnsemblRapid:ENSBTAG00070019667
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RBL2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (21801909..21853186)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene craniofacial development protein 2-like Neighboring gene CHD9 neighbor Neighboring gene chromodomain helicase DNA binding protein 9 Neighboring gene AKT interacting protein Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene RPGRIP1 like Neighboring gene transfer RNA tryptophan (anticodon CCA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC154964

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    retinoblastoma-like protein 2
    Names
    retinoblastoma-like 2 (p130)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098073.1 → NP_001091542.1  retinoblastoma-like protein 2

      See identical proteins and their annotated locations for NP_001091542.1

      Status: PROVISIONAL

      Source sequence(s)
      BC140608
      UniProtKB/TrEMBL
      A0A3Q1M1Y7, A5D7M0
      Related
      ENSBTAP00070026747.1, ENSBTAT00070044442.1
      Conserved Domains (3) summary
      pfam01857
      Location:835 → 1017
      RB_B; Retinoblastoma-associated protein B domain
      pfam01858
      Location:417 → 609
      RB_A; Retinoblastoma-associated protein A domain
      pfam11934
      Location:104 → 236
      DUF3452; Domain of unknown function (DUF3452)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      21801909..21853186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005218649.5 → XP_005218706.1  retinoblastoma-like protein 2 isoform X1

      See identical proteins and their annotated locations for XP_005218706.1

      UniProtKB/TrEMBL
      A0A3Q1M1Y7, A5D7M0
      Conserved Domains (3) summary
      pfam01857
      Location:835 → 1017
      RB_B; Retinoblastoma-associated protein B domain
      pfam01858
      Location:417 → 609
      RB_A; Retinoblastoma-associated protein A domain
      pfam11934
      Location:104 → 236
      DUF3452; Domain of unknown function (DUF3452)

    2. XM_005218651.5 → XP_005218708.1  retinoblastoma-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0AAA9S8J4
      Conserved Domains (3) summary
      pfam01857
      Location:619 → 801
      RB_B; Retinoblastoma-associated protein B domain
      pfam01858
      Location:201 → 393
      RB_A; Retinoblastoma-associated protein A domain
      pfam11934
      Location:1 → 20
      DUF3452; Domain of unknown function (DUF3452)
    Nucleotide Protein Strain
    Heading Accession and Version

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