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    RT1-M1-4 RT1 class I, locus M1, gene 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294213, updated on 9-Dec-2024

    Summary

    Official Symbol
    RT1-M1-4provided by RGD
    Official Full Name
    RT1 class I, locus M1, gene 4provided by RGD
    Primary source
    RGD:1359375
    See related
    EnsemblRapid:ENSRNOG00000075316 AllianceGenome:RGD:1359375
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    H2-M11
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 7.6) See more
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    Genomic context

    See RT1-M1-4 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (1895440..1903169, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (1891365..1893585, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (2387596..2391253, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene RT1 class I, locus M7, pseudogene Neighboring gene RT1 class I, M1, gene 5 Neighboring gene RT1 class I, locus M1, gene 3, pseudogene Neighboring gene Trim39 pseudogene Neighboring gene RT1 class I, locus M1, gene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables peptide antigen binding  
    enables signaling receptor binding  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane  
    is_active_in extracellular space  
    located_in membrane  

    General protein information

    Preferred Names
    RT1 class I, locus M1, gene 4
    Names
    histocompatibility 2, M region locus 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008850.1 → NP_001008850.1  RT1 class I, locus M1, gene 4 precursor

      See identical proteins and their annotated locations for NP_001008850.1

      Status: PROVISIONAL

      Source sequence(s)
      BX883051
      UniProtKB/TrEMBL
      A0A8I6GK27, A6KR93, Q6MFZ2
      Related
      ENSRNOP00000092191.2, ENSRNOT00000038626.6
      Conserved Domains (2) summary
      cd07698
      Location:207 → 299
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      cl08246
      Location:25 → 203
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      1895440..1903169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063278995.1 → XP_063135065.1  RT1 class I, locus M1, gene 4 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AK64, A0A8I6GK27, A6KR93
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