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    Slc35e2b solute carrier family 35, member E2B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313765, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc35e2bprovided by RGD
    Official Full Name
    solute carrier family 35, member E2Bprovided by RGD
    Primary source
    RGD:1309076
    See related
    EnsemblRapid:ENSRNOG00000062404 AllianceGenome:RGD:1309076
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Slc35e2
    Summary
    Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to several human genes including SLC35E2B (solute carrier family 35 member E2B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 219.1), Kidney (RPKM 93.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc35e2b in Genome Data Viewer
    Location:
    5q36
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (171465222..171493317)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (166185166..166211055)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (173024335..173050228)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene NAD kinase Neighboring gene ATP synthase peripheral stalk subunit d, pseudogene 1 Neighboring gene uncharacterized LOC134487048 Neighboring gene cyclin-dependent kinase 11B Neighboring gene ribosomal protein L27A like 10 Neighboring gene matrix metallopeptidase 23

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Cui W, et al. Sci Rep, 2016 Nov 21. PMID 27869233, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst hatching ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 35 member E2B
    Names
    solute carrier family 35, member E2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107998.1 → NP_001101468.1  solute carrier family 35 member E2B

      See identical proteins and their annotated locations for NP_001101468.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473968
      UniProtKB/TrEMBL
      A6IUQ8, D4A0R5
      Conserved Domains (2) summary
      pfam03151
      Location:73 → 368
      TPT; Triose-phosphate Transporter family
      cl23754
      Location:183 → 367
      EamA; EamA-like transporter family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      171465222..171493317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008764361.4 → XP_008762583.1  solute carrier family 35 member E2B isoform X2

      Conserved Domains (1) summary
      pfam03151
      Location:73 → 326
      TPT; Triose-phosphate Transporter family

    2. XM_006239573.4 → XP_006239635.1  solute carrier family 35 member E2B isoform X3

      Conserved Domains (1) summary
      pfam03151
      Location:73 → 326
      TPT; Triose-phosphate Transporter family

    3. XM_006239572.5 → XP_006239634.1  solute carrier family 35 member E2B isoform X1

      See identical proteins and their annotated locations for XP_006239634.1

      UniProtKB/TrEMBL
      A6IUQ8, D4A0R5
      Related
      ENSRNOP00000099246.1, ENSRNOT00000095515.2
      Conserved Domains (2) summary
      pfam03151
      Location:73 → 368
      TPT; Triose-phosphate Transporter family
      cl23754
      Location:183 → 367
      EamA; EamA-like transporter family
    Nucleotide Protein Strain
    Heading Accession and Version

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