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    polr2c RNA polymerase II subunit C [ Danio rerio (zebrafish) ]

    Gene ID: 334669, updated on 9-Dec-2024

    Summary

    Official Symbol
    polr2cprovided by ZNC
    Official Full Name
    RNA polymerase II subunit Cprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6609
    See related
    Ensembl:ENSDARG00000033596 AllianceGenome:ZFIN:ZDB-GENE-030131-6609
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56285; wu:fk48d01
    Summary
    Predicted to enable DNA-directed 5'-3' RNA polymerase activity and protein dimerization activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to act upstream of or within DNA-templated transcription. Predicted to be part of RNA polymerase II, core complex. Orthologous to human POLR2C (RNA polymerase II subunit C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See polr2c in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (14369496..14378869, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (14273096..14282469, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene actin, epsilon 1 Neighboring gene SH3 and multiple ankyrin repeat domains 2b Neighboring gene coenzyme Q9 homolog (S. cerevisiae) Neighboring gene cytokine induced apoptosis inhibitor 1 Neighboring gene protein arginine methyltransferase 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to RNA polymerase II activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerase II subunit RPB3
    Names
    polymerase (RNA) II (DNA directed) polypeptide C
    NP_001161428.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167956.2NP_001161428.1  DNA-directed RNA polymerase II subunit RPB3

      See identical proteins and their annotated locations for NP_001161428.1

      Status: VALIDATED

      Source sequence(s)
      BM571522, EH524379, EH555113
      UniProtKB/TrEMBL
      A0A8M1NVN0, Q7ZV11
      Related
      ENSDARP00000043811.4, ENSDART00000043812.5
      Conserved Domains (2) summary
      cd07031
      Location:7266
      RNAP_II_RPB3; RPB3 subunit of Eukaryotic RNA polymerase II
      smart00662
      Location:19260
      RPOLD; RNA polymerases D

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      14369496..14378869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395192.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      420935..430308 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395369.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      113276..122649 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)